Cold Symptom

Kholodenko Symptom: Description and Meaning in Neuropathology

The Kholodenko symptom, named after the outstanding Soviet neurologist Mikhail Ivanovich Kholodenko (1906-1979), is one of the important clinical characteristics used in the diagnosis of nervous disorders. This symptom is usually observed in certain pathological conditions associated with disorders of the peripheral nervous system.

Kholodenko was known for his research in neurology and nervous pathology, and his contributions to the understanding of nervous disorders remain significant. Kholodenko's symptom was one of many clinical signs that he described and used for more accurate diagnosis and classification of neurological diseases.

The description of the Kholodenko symptom may vary depending on the specific pathology, but in general it is associated with changes in the body's response to cold. Typically, the symptom manifests itself as follows: while monitoring the patient, the doctor applies a cold stimulus to a specific area of ​​the body, for example, using ice or alcohol compresses. Under normal conditions, there is a typical reaction to cold that includes constriction of blood vessels and changes in skin color. However, patients with Cholodenko's symptom may experience an abnormal response, such as absent or weakened vasoconstriction, a disproportionate response to cold, or a long time to restore normal circulation.

Kholodenko's symptom can be characteristic of various neurological conditions, including neuropathies, neuritis, neuralgia and other pathologies associated with damage to the peripheral nervous system. It can serve as an important indicator for differential diagnosis of the etiology of neurological symptoms and help determine what additional investigations and treatment interventions may be necessary.

It is important to note that the Kholodenko symptom is just one of many clinical signs that can be used in neurological practice. To make an accurate diagnosis and determine optimal treatment, a comprehensive approach is required, including anamnesis, physical examination, laboratory and instrumental studies.

The Kholodenko symptom remains a significant element in clinical neurological examination and continues to be used in modern medical practice. BlagKholodenko Symptom: Description and Meaning in Neuropathology

The Kholodenko symptom, named after the outstanding Soviet neurologist Mikhail Ivanovich Kholodenko (1906-1979), is one of the important clinical characteristics used in the diagnosis of nervous disorders. This symptom is usually observed in certain pathological conditions associated with disorders of the peripheral nervous system.

Mikhail Ivanovich Kholodenko was known for his research in the field of neurology and nervous pathology. He made significant contributions to the understanding of nervous disorders and described many clinical features used to more accurately diagnose and classify neurological diseases.

The cold symptom can manifest itself differently depending on the specific pathology, but it is usually associated with changes in the body's response to cold. Doctors use this symptom to identify abnormalities in a patient's response to cold stimuli. Typically, a normal reaction to cold involves constriction of blood vessels and a change in skin color. However, patients with Cholodenko's symptom may experience absent or weakened vasoconstriction, an inadequate response to cold, or a delayed restoration of normal circulation.

Kholodenko's symptom can be characteristic of various neurological conditions, including neuropathies, neuritis, neuralgia and other pathologies associated with damage to the peripheral nervous system. It can serve as an important indicator for differential diagnosis of the etiology of neurological symptoms and help determine what additional investigations and treatment interventions may be necessary.

However, it is important to note that the Kholodenko symptom is only one of many clinical signs that can be used in neurological practice. To make an accurate diagnosis and determine optimal treatment, a comprehensive approach is required, including anamnesis, physical examination, laboratory and instrumental studies.

The Kholodenko symptom remains a significant element in clinical neurological examination and continues to be used in modern medical practice. It allows doctors to more accurately identify peripheral nervous system disorders and develop an appropriate treatment plan for patients suffering from neurological diseases.



Kholodenko V.I. (author of Kholodenko's symptom). The symptom was developed in 1966 by the Soviet neurologist V. Kholodenko. It is a classic manifestation of a cerebral vascular accident (stroke, acute cerebrovascular accident)

Considering the vast area of ​​innervation of the limb with post-stroke hemiparesis, hypotension and spasticity in the paralyzed arm, the rapid restoration of function of the paretic limbs after electrical myostimulation of the limbs during the IV administration of pentoxyl and long-term use of miotic drugs (aminophylline, papaverine) and clonidine. Long-term observation data indicate that EMS can compensate for the inferiority of the neuromuscular system and improve the function of paremic limbs in patients with consequences of stroke.

KHOLODENKO VIKTOR IVANOVYCH. From January 1950-1952 - head. Department of Therapy, Polotsk Medical Institute. On September 25, 1948 he defended his doctoral dissertation (“Intermittent kidney function in mice, their breeding and creation of new breeds.” August 28, 1936 - 68 years ago, a Soviet physician and scientist was born. Viktor Ivanovich Kholodenko was born 18 (old style December 6, 1898) in a Swiss worker's family, 8 months after