Diazepam, also known by many synonyms, is a tranquilizer from the group of benzodiazepine derivatives. This drug is produced by the Austrian company Merkle GmbH and is widely used in medical practice.
Diazepam is available in a variety of dosage forms, including tablets, injections, and suppositories. The active ingredient is diazepam, which has a sedative, anticonvulsant and muscle relaxant effect.
Indications for the use of diazepam include neuroses, neurasthenia, hysteria, reactive depression, agoraphobia, insomnia associated with a violation of the phase of falling asleep, Meniere's disease, spastic paralysis, withdrawal syndrome in patients with alcoholism, status epilepticus, epilepsy, premedication before surgical interventions and endoscopic manipulations, and also LSD poisoning.
There are contraindications to the use of diazepam, including hypersensitivity to the drug, acute liver and kidney diseases with impaired function, myasthenia gravis, angle-closure glaucoma, the first trimester of pregnancy and breastfeeding.
When using diazepam, side effects may occur, such as addiction, paradoxical reactions (development of anxiety, hallucinations, convulsions, insomnia), decreased reaction speed and concentration, drowsiness, deterioration of short-term memory, ataxia, dysarthria, headache, dizziness, hypotension, bradycardia , with long-term use, liver and kidney damage, intestinal atony, decreased libido and potency, reactions at the injection site, withdrawal syndrome and aftereffect syndrome (decreased performance, muscle weakness), allergic reactions.
Diazepam may also interact with other drugs, potentiating their effects. For example, diazepam enhances the effect of alcohol, anticonvulsants and antihypertensives, analgesics and hypnotics. MAO inhibitors, analeptics and psychostimulants, on the contrary, reduce its activity.
If an overdose of diazepam occurs, symptoms such as drowsiness, impaired consciousness, coma and decreased reflexes may occur. Treatment includes gastric lavage, intravenous fluids and antagon