Digoxin TFT: description, application and side effects
Digoxin TFT is a cardiotonic drug that is used to treat various cardiovascular diseases. The drug is produced by the Tallinn Pharmaceutical Plant in Estonia and contains the active substance digoxin. In this article we will look at the main characteristics of the drug, its use, side effects and special instructions.
Characteristics of the drug
Digoxin TFT belongs to the group of cardiotonic drugs - cardiac glycosides. It is used to improve the contractile function of the heart, reduce the load on the heart and improve blood circulation. The drug is available in the form of an injection solution with a digoxin concentration of 0.25 mg/ml.
Application
Digoxin TFT is used to treat the following conditions:
- Congestive circulatory failure (without hemodynamically significant obstruction of the cardiac outflow tract)
- Atrial fibrillation
- Supraventricular paroxysmal tachycardia
- Atrial flutter
Contraindications
Glycoside intoxication is the main contraindication to the use of digoxin TFT. This condition occurs with an overdose of the drug and is manifested by symptoms such as arrhythmia, AV block, vomiting and nausea.
Side effects
The following side effects may occur when using digoxin TFT:
- Nausea and vomiting
- Anorexia
- Bradycardia
- Ventricular extrasystole
- AV block
- Headache and dizziness
- Impaired color vision, decreased visual acuity, scotomas, macro- and microopsia
- Gynecomastia with long-term use
Interaction
Digoxin TFT may interact with other drugs and cause unwanted effects. For example, adrenomimetics can increase the likelihood of developing arrhythmia, antiarrhythmic and anticholinesterase drugs - bradycardia, and glucocorticoids, saluretics and other drugs that promote potassium loss can cause glycoside intoxication. Aminazine reduces the cardiotonic effect, and laxatives, antacids and products containing aluminum, bismuth and magnesium can reduce the absorption of digoxin. Rifampicin and sulfasalazine accelerate the metabolism of the drug.
Overdose
In case of overdose