Dilanacin

Country of origin: Germany

Pharm-Group: Cardiotonic drugs - cardiac glycosides

Manufacturers: Arzneimittelwerk Dresden GmbH (Germany)

International name: Digoxin

Synonyms: Digoxin, Digoxin Nycomed, Digoxin TFT, Digoxin-Teva, Dilacor, Lanikor, Lanoxin

Dosage forms: tablets 0.25 mg

Composition: Active substance - digoxin.

Indications for use: Congestive circulatory failure (without hemodynamically significant obstruction of the outflow tract of the heart), atrial fibrillation, supraventricular paroxysmal tachycardia, atrial flutter.

Contraindications: Glycoside intoxication.

Side effects: Nausea, vomiting, anorexia, bradycardia, ventricular extrasystole, AV block, headache, dizziness. Possible disturbance of color vision, decreased visual acuity, scotomas, macro- and microopsia, and with prolonged use - gynecomastia.

Interaction: Adrenomimetics increase the likelihood of developing arrhythmia, antiarrhythmic and anticholinesterase drugs - bradycardia, glucocorticoids, saluretics and other drugs that promote potassium loss, calcium drugs - glycoside intoxication. Aminazine reduces the cardiotonic effect, laxatives, antacids, products containing aluminum, bismuth, magnesium - absorption. Rifampicin and sulfasalazine speed up metabolism.

Overdose: Symptoms: Arrhythmia, AV block, vomiting, nausea. Treatment: potassium preparations, unithiol, ethylenediaminetetraacetate.

Special instructions: Combine with diuretics and sympathomimetics with caution. Co-administration with amphotericin B and calcium supplements should be avoided.

Literature:

1. Encyclopedia of Medicines, 2003
2. Encyclopedia of Medicines, 2002.
3. Encyclopedia of Medicines, 1999.