Diursan: a combination diuretic for the treatment of hypertension and edema
Diursan is a combined diuretic that is used to treat hypertension, edema of cardiac, renal and hepatic origin, as well as ascites in liver cirrhosis. The drug is manufactured by Tad Pharmaceuticals Wecker GmbH in Germany and contains hydrochlorothiazide and amiloride.
Hydrochlorothiazide is a thiazide diuretic that increases the excretion of sodium, chloride, and water from the body. Amiloride is a potassium-sparing diuretic that reduces potassium excretion from the body. The combined use of these two diuretics allows one to achieve a more pronounced and stable diuretic effect.
The drug is available in the form of 5 mg tablets. Diursan has several synonyms: Amyloside, Amiloretic, Diursan mite, Moduretic, Ecodurex.
However, like any other drug, Diursan has its contraindications and side effects. The drug is not recommended for use in case of hypersensitivity to its components, simultaneously with antikaliuretic drugs, in severe renal failure, during pregnancy and lactation, as well as under the age of 18 years.
Among the side effects that may occur when taking Diursan, there may be hyperkalemia, nausea, anorexia, skin rashes, headache, dizziness, gastrointestinal disorders, metabolic disorders, depression, insomnia, drowsiness, dysuria, nocturia, enuresis .
It is also important to consider the possible interaction of Diursan with other medications. For example, the hypokalemic effect of Diursan may be enhanced when used simultaneously with corticosteroids. Combined use with cardiac glycosides can increase the toxicity of the latter, and with antidiabetic drugs - weaken the effect of the latter. This drug should not be prescribed simultaneously with potassium-sparing and potassium-containing drugs.
In conclusion, Diursan is an effective combination diuretic that is widely used for the treatment of hypertension and edema. However, before you start taking this drug, you must consult your doctor and find out about possible contraindications and side effects. It is also important to follow dosage recommendations and not exceed the recommended dose.