Excretion Tubular Maximum: An indicator of the functional state of the kidneys
Introduction:
Maximum tubular excretion (TEM) is an important indicator used to assess the functional status of the kidneys. It represents the amount of para-aminohippuric acid or diodrast (cardiotrast) excreted in the urine in an average of 1 minute, normalized to the standard volume of renal blood flow. ECM is one of the indicators of the kidneys' ability to filter and excrete substances from the body.
Description and meanings of ECM:
ECM is measured by injecting a certain amount of para-aminohippuric acid or diodrast into the patient's body and then measuring its concentration in the urine. This allows you to evaluate how efficiently your kidneys process and excrete these substances. With high ECM, the patient has an increased ability of the kidneys to concentrate and excrete these substances, which indicates good renal tubular function.
A standard renal blood flow volume is used to normalize the ECM value. It is defined as the volume of blood passing through the kidneys per unit of time. This allows comparison of ECM between different patients, taking into account individual differences in renal blood flow.
Use of ECM in clinical practice:
ECM is a useful tool in the diagnosis and monitoring of various renal diseases. Decreased ECM may indicate decreased kidney function, such as chronic kidney failure or acute kidney injury. Increased ECM may be associated with impaired reabsorption of substances in the renal tubules or with other pathological conditions such as diabetic nephropathy.
In addition, ECM can be used to evaluate the effectiveness of medications that affect kidney function. Some medications may increase or decrease ECM, which may be an indicator of their effect on renal function.
Limitations and prospects of research:
Although ECM is an important indicator of renal function, it should be noted that it represents only one aspect of renal function. A complete assessment of the kidneys requires taking into account other parameters such as glomerular filtration, reabsorption and secretion of other substances.
Future studies may focus on refining ECM values for different patient populations, developing more accurate measurement techniques, and determining the relationship between ECM and other measures of renal function. This may help improve the diagnosis and monitoring of renal diseases and optimize the use of drugs that affect renal function.
Conclusion:
Maximum tubular excretion (TME) is an important indicator of the functional state of the kidneys. It provides information about the kidneys' ability to filter and eliminate substances from the body. The use of ECM allows the diagnosis and monitoring of renal diseases, as well as the evaluation of the effectiveness of medications. However, to fully assess renal function, other parameters must be taken into account. Further research in this area may lead to more accurate ECM measurement techniques and improved diagnosis and treatment of kidney disease.
Note: Duplicates were found in the description provided. I used the information from the original description to write the article.
Maximum tubular excretion (Emax) is one of the most important indicators used to assess the functional state of the kidneys. This indicator reflects the ability of the kidneys to quickly and effectively remove toxic substances and metabolites from the body, as well as prevent