Endothelial Stellate Cell

Endothelial Stellate Cell: Structure and Function

Endothelial cells are specialized cells that line the inner surface of blood vessels and the heart. They play an important role in maintaining physiological functions of the body, such as blood pressure regulation, immunity and gas exchange. Endothelial stellate cell (endotheliocytus stellatus) is one of the types of endothelial cells that has a special structure and function.

The structure of the endothelial stellate cell looks like a star with many elongated projections in different directions. These projections are called pseudopodia and help the cell attach to other cells and the matrix of the extracellular space. In addition, pseudopodia increase the contact surface between cells, which promotes more efficient metabolism and information.

The functions of the endothelial stellate cell include regulation of the permeability of the vascular wall, protection against infections and participation in hematopoiesis. Endothelial cells control the permeability of the vascular wall by regulating the size of the gaps between the cells. This allows them to control blood flow and the exchange of substances between blood and tissues. Endothelial cells also play an important role in the body's immune defense by releasing molecules that attract immune cells to the site of infection or injury.

In addition, endothelial cells can participate in hematopoietic processes. Some studies have shown that endothelial cells can differentiate into hematopoietic stem cells or give rise to blood cells such as platelets or red blood cells. This makes the endothelial stellate cell an important object of study in studies of hematopoiesis and the treatment of diseases associated with a lack of hematopoietic cells.

In conclusion, the stellate endothelial cell is a unique type of endothelial cell that plays an important role in maintaining the physiological functions of the body. Its structure and functions allow the cell to regulate the permeability of the vascular wall, protect the body from infections and participate in the processes of hematopoiesis. Further research will allow us to better understand the role of the endothelial stellate cell in the body and use its potential to develop new treatments for various diseases.

Endothelial stellate cell (lat. endothelia stellata) is a type of endothelial cell of blood vessels. These cells form the inner layer of the vessel wall, which protects the vessels from damage and performs many other functions.

Endothelial stellate cells get their name because they have a characteristic star shape. They have many processes that help cells communicate with each other and perform various functions. Their shape allows them to occupy a larger area than normal endothelial cells, making them very important for maintaining vessel shape and protecting vessels from damage.

Under normal conditions, endothelial stellate cells produce growth factors that stimulate the growth of other endothelial and connective cells. This helps maintain the integrity of the vessel wall and maintain its functionality.

However, in certain diseases, such as atherosclerosis or diabetes, endothelium can become damaged and even proliferate. This leads to an increase in the number of endothelial stellate cells and changes in their activity, which can impair blood flow and cause problems with the cardiovascular system.

It is also known that endothelial stellate cells have the ability to regulate fluid circulation in the body, as well as respond to various changes in the internal environment of the body.