Filtration Fraction of Renal Blood Flow

The filtration fraction of the kidney blood flow is one of the indicators of kidney function. Normally, the filtration fraction should be about 70-80%, which indicates sufficient filtration of blood in the renal tubules. If this indicator decreases, this may indicate impaired renal function and the presence of diseases such as glomerulonephritis, nephrotic syndrome or diabetic nephropathy. The study of the filtration fraction is carried out on the basis of urine analysis data.

Urine filtration occurs in the glomeruli and tubules of the kidneys. The glomeruli filter the blood, separating from it substances that the body does not need. The tubules release substances necessary for the body back into the blood and take part in maintaining acidity and acid-base balance. The filtration capacity of the kidneys is determined by the amount of fluid filtered. This depends on how well the glomerulus functions, as well as on the condition of the tubules in which the fluid is cleared and released back into the bloodstream.

One of the reasons for a decrease in the filtration fraction may be damage or disruption of the functioning of the glomeruli. For example, this occurs in chronic glomerulonephritis or other inflammatory kidney diseases. Also, a decrease in the filtration fraction is observed with severe dilation of the renal vessels - nephroangiosclerosis. With this disease, the walls of blood vessels thicken, forming connective tissue, which interferes with the normal functioning of the kidneys. In addition, the filtration fraction may decrease when