Fraxiparin

Fraxiparine: an effective direct-acting anticoagulant

Fraxiparine (international name - nadroparin calcium) is a representative of the group of direct-acting anticoagulants. This medication is manufactured in France by Sanofi Winthrop Industrie. Fraxiparine is widely used in clinical practice due to its anticoagulant properties.

Fraxiparine is available in several dosage forms, including subcutaneous solutions and injections of various strengths such as 7500 IU, 15000 IU, 25000 IU, 2850 IU, 5700 IU and 3800 IU Anti-Xa. This allows the drug to be prescribed according to the individual needs of the patient.

The main active substance in Fraxiparine is calcium nadroparin. This component has pronounced anticoagulant properties, helping to prevent the formation of blood clots in the body.

The use of Fraxiparine is recommended in the following cases:

1. Deep vein thrombosis: Fraxiparine is effective in the prevention and treatment of deep vein thrombosis, which can occur after surgical procedures, such as orthopedic, oncological and general surgery.

2. Pulmonary embolism: Fraxiparine is used for the prevention and treatment of thromboembolic complications associated with thrombus formation in the pulmonary artery.

3. Acute coronary syndrome: The drug may be prescribed to patients with acute coronary syndrome to prevent blood clots in the coronary arteries and improve blood flow to the heart.

4. Prevention of thrombosis in high-risk patients: Fraxiparine is used to prevent thrombosis in high-risk patients, such as those undergoing hemodialysis or hemofiltration for chronic renal failure.

Fraxiparine should not be used in the following cases:

1. Hypersensitivity to the drug.

2. Bleeding or hemorrhage in the brain (except for systemic embolism).

3. Acute bacterial endocarditis, pericarditis.

4. Exacerbation of peptic ulcer of the stomach and duodenum.

5. Injuries to the central nervous system.

6. Condition after spinal puncture or radiation therapy.

7. Thrombocytopenia with a positive test for thrombocytopenic purpura (immune thrombocytopenia).

Fraxiparine is generally well tolerated by patients, but some side effects may include bleeding, rash, itching, increased liver enzymes, and increased blood potassium levels. If you experience any side effects or complications, it is important to contact your doctor.

The dosage of Fraxiparine depends on many factors, including the individual characteristics of the patient, the type and severity of the disease. Only a doctor can determine the correct dose, duration of treatment and method of administration of the drug.

It is important to follow your doctor's instructions and not change the dosage or regimen without his consent.

Fraxiparine is a powerful anticoagulant and its use requires attention and supervision from a medical professional. If you have any questions or concerns about the use of Fraxiparine, it is recommended that you contact your doctor or pharmacist for more detailed information and advice.