Gamma Inhibitor

Gamma Inhibitor: properties and application

A gamma inhibitor is a thermostable mucoprotein that is contained in the gamma globulin fraction of blood serum and has the ability to inhibit the activity of orthomyxoviruses, including hemagglutinating activity.

Orthomyxoviruses, including influenza viruses, are important pathogens for humans and animals. They can cause a wide range of illnesses, from mild colds to severe infections such as pneumonia and encephalitis. Gamma inhibitors may be useful in the fight against these viruses because they can inhibit their hemagglutinating activity, which prevents their ability to adhere to cells and infect the body.

In addition to their antiviral properties, gamma inhibitors may also play a role in the body's immune system. They can participate in the regulation of the activity of immune cells and influence the process of adaptation of the immune system to new infections and viruses.

The study of gamma inhibitors and their applications in medicine is an active area of ​​research. Some studies have shown that gamma inhibitors may be useful in the treatment of influenza and other orthomyxovirus infections, as well as in the prevention of these diseases.

However, despite the promise of gamma inhibitors, their use in clinical practice is still limited. Additional research is needed to determine the effectiveness and safety of these drugs, as well as to determine optimal dosages and schedules for their use.

In conclusion, gamma inhibitors represent a promising class of drugs that may be useful in the treatment and prevention of orthomyxovirus infections, as well as in regulating the body's immune system. Although more research is needed to determine their effectiveness and safety, gamma inhibitors represent an important area of ​​research in the fields of medicine and immunology.

Gamma inhibitor is a thermostable protein-polysaccharide compound of the gamma globule type, isolated from the serum of pregnant women and animals, exhibits antiviral, antibacterial, antifungal effects, immunomodulatory effects, prevents the oxidation of pathologically altered proteins and fats (antioxidase effect), activates the antimicrobial cascade, stimulates the growth of resident macrophages and the activity of monocytes.

Gamma inhibitors are used for the prevention and treatment of influenza, acute respiratory infections, pneumonia, chlamydia, mycoplasmosis, HSV, EBV, and CMV infections. In severe forms of influenza and acute respiratory viral infections, antihistamine activity in humans is important, manifested by an improvement in the patient’s condition (introducing the patient into a “tonic crisis”). In vitro studies have shown that when gamma inhibitors come into contact with capsid fragments of highly pathogenic strains of the SARS-CoV-2/COVID-19 virus, blocking of peptide bonds occurs and the formation of a protein-free state of virus capsid fragments when its adhesion to ACE2 receptor cells is blocked. This allows the use of gamma inhibitors for treatment during the COVID-19 pandemic.