Country of origin - Germany
Pharm-Group - Antihypertensive drugs affecting the vasomotor centers of the brain
Manufacturers - Arzneimittelwerk Dresden GmbH (Germany)
International name - Clonidine
Synonyms - Apo-Clonidine, Barklid, Catapresan, Clonidine, Clonidine-M, Chlofazolin
Dosage forms - tablets 0.075 mg, tablets 0.3 mg, solution for injection 0.15 mg/ml
Composition - Active ingredient - Clonidine.
Indications for use:
- Hypertensive crises, arterial hypertension
- Myocardial infarction in the acute period (in the absence of signs of cardiogenic shock and a concomitant increase in blood pressure)
- Primary open-angle glaucoma with high and moderate intraocular pressure
- Withdrawal syndrome of opium addiction (as part of complex therapy)
Contraindications:
- Hypersensitivity
- Cardiogenic shock
- Arterial hypotension
- Obliterating peripheral artery disease
- AV block II-III degree
- Sick sinus syndrome
- Depressive states
Restrictions on use:
- Pregnancy
- Breastfeeding (breastfeeding should be avoided)
- Work that requires a quick mental or physical reaction
Side effect:
- Dry mouth
- Constipation
- Weakness
- Drowsiness
Interaction:
- The hypotensive effect is weakened by nifedipine
- When used with antipsychotics, there is a mutual increase in sedative manifestations, and severe depressive disorders may occur.
Overdose:
It manifests itself as a disturbance of consciousness, collapse; the state of acute poisoning is characterized by bradycardia, widening of the QRS complex, possible slowing of AV conduction and early repolarization syndrome. Treatment is symptomatic.
Special instructions: No data available.
Literature: Encyclopedia of Medicines 2003