Hemoglobinuria Drug

Hemoglobin or not hemoglobin?

Hemoglobin presentation

_You probably know a lot about hemoglobin or blood cells - they are erythrocytes and are part of red blood cells. Red blood cells contain iron-containing hemoglobin and the cofactor protein heme..._

However, there is another variant of hemoglobin - globioglobin. This is an alternative form of hemoglobin that usually has a lower value in the blood. Globioglobins pass through the kidneys and are excreted in the urine, which leads to the appearance of bloody urine - hemoglobinuria. This term may not always be easy to understand, but for the sake of brevity, let's just call it "hemoglobinuria."

Drug hemolysis can occur when drugs have been prescribed that can lead to the destruction of red blood cells - a hemolytic condition. These drugs can cause not only hemolysis, but also toxic damage to kidney endothelial cells, which can lead to more severe complications such as renal tubular necrosis and even acute renal failure.

Types of diseases of the globocyte circle

There are two types of global globin medicine – acquired and congenital. Acquired globulin is caused by long-term abuse of certain drugs such as isoniazid, captopril, sulfonamides, and chloramphenicol. Congenital globular glucoseopathy can exist as a genetic variant, occurring in several different forms. The pemphric globular crescent pattern occurs due to the presence of a mutation in the tyrant gene.