Epidermolytic hyperkeratosis

Epidermolytic hyperkeratosis: causes, symptoms and treatment

Epidermolytic hyperkeratosis, also known as hyperkeratosis epidermolytica, is a dermatological disorder characterized by excessive formation of dead skin cells. This condition can have various causes and manifestations, and requires an integrated approach to treatment.

One of the main causes of epidermolytic hyperkeratosis is genetic predisposition. Most cases of this disease are associated with inherited mutations in genes that control the normal differentiation and keratinization of epidermal cells. This leads to disruption of the exfoliation process and accumulation of dead cells on the surface of the skin.

Symptoms of epidermolytic hyperkeratosis may vary depending on the severity of the disease. However, common manifestations include rough, thick and rough skin that is prone to cracks and ulcers. Rough spots or plates on the skin are often observed, especially on the elbows, knees, feet and hands. Some patients may experience itching or discomfort in the affected areas.

Treatment of epidermolytic hyperkeratosis is aimed at reducing keratinization of the skin and improving its condition. It is important to use gentle products to cleanse the skin and avoid aggressive mechanical influences such as strong rubbing or scrubbing. Regular use of moisturizers helps soften dead skin and reduce dry skin.

Keratolytic creams or ointments containing urea, salicylic acid, or mild alpha hydroxy acids can help remove dead skin cells and improve skin texture. In some cases, topical retinoids or systemic medications may be necessary to control keratinization.

It is also important to maintain a good skin care routine and avoid factors that can aggravate skin conditions, such as prolonged exposure to sunlight or chemical irritants.

Epidermolytic hyperkeratosis is a chronic condition, and treatment is aimed at relieving symptoms and improving the patient's quality of life. Regular monitoring by a dermatologist and following skin care recommendations will help monitor skin conditions and prevent flare-ups.

In conclusion, epidermolytic hyperkeratosis is a dermatological disorder characterized by the excessive formation of keratinized cells in the skin. Genetic predisposition plays an important role in the development of this condition. Treatment includes using gentle cleansers, moisturizing, using keratolytic agents, and maintaining a good skin care regimen. Regular monitoring by a dermatologist and following the recommendations will help control the skin condition and improve the patient’s quality of life.