Histamine

Histamine is a compound derived from the amino acid histidine. Present in almost all tissues of the body, associated with basophilic leukocytes and mast cells. Histamine has a pronounced pharmacological activity, causing local dilation of blood vessels (arterioles and venules), and also increases epithelial permeability (ed.) and contraction of smooth muscles (for example, in the lungs). It is an important mediator of inflammation and is released in large quantities after any damage to the skin (resulting from animal venom or toxic substances), resulting in a characteristic skin reaction (inflammation and redness) in the affected area. Histamine is also released during anaphylactic and allergic reactions, including asthma, contributing to their further development. See also Anaphylaxis, Antihistamine.

Histamine is a biologically active substance that plays an important role in the regulation of many physiological processes in the body. It is synthesized in the cells of various tissues and organs, including the brain, heart, lungs, skin and other systems.

Histamine is a derivative of the amino acid histidine. It has pronounced pharmacological properties, including dilation of blood vessels and increased epithelial permeability. Histamine is involved in the development of allergic reactions and inflammatory processes, and also plays an important role in protecting the body from infections and other pathogenic factors.

Normally, histamine is released in small quantities and controls many processes in the body, but under certain conditions its level can increase significantly. For example, histamine can be released when the skin is damaged or when poisons enter the body. In such cases, histamine causes the development of characteristic skin reactions such as redness and itching.

Histamine also plays an important role in the development of anaphylactic reactions. In this case, a large amount of histamine is released, which leads to the development of allergic symptoms and further deterioration of the body’s condition.

To treat allergic reactions and inflammatory processes, antihistamines are used, which block the action of histamine on receptors in tissues. These drugs help lower histamine levels and reduce the occurrence of allergic reactions.

In addition, histamine has other functions in the body, such as regulating blood pressure, controlling blood glucose levels and participating in digestive processes. Therefore, the study of histamine and its role in various physiological processes is a current trend in modern medicine.

Histamine is a biologically active chemical compound present in many tissues of the body. It arises from the amino acid histedine and binds to basophilic leukocyte cells and mast tissue. When activated, histamine can cause a wide range of functions in the body, including vasodilation and increased epithelial tissue permeability, smooth muscle contraction, and inflammation.

In more cases, histamine is released when the skin is injured as a result of exposure to toxic or chemical substances. This leads to the development of a local inflammatory reaction, which is manifested by redness and swelling of the affected area. Anaphylaxis and allergic reactions also release histamine and contribute to the development and progression of inflammation.

Histamine plays an important role in the development and maintenance of inflammation in the body. It is also involved in allergic reactions, where it may contribute to the spread of disease. However, in small quantities, histamine is used as a medicine in the treatment of allergic conditions. In the medical industry, histamine is widely used to treat allergies and asthma.

However, it must be remembered that exceeding the normal concentration of histamine in the blood or histamine intoxication can be hazardous to health. An overdose of histamine can cause insomnia, depression, and even lung collapse. In addition, some people have a certain sensitivity to histamine, which can lead to more serious complications when using histamine-based medications.

Conclusion: histamine has important functions in the human body and is involved in various physiological processes. However, its excess may