Globulin Antihemophilic

Globulins and blood clotting factors.

I’ll say right away that there are a lot of monotonous and repetitive words in medical terminology, but the fact is that the use of various kinds of abbreviations improves the readability and speed of the doctor’s response. Globulin and factor are two different classes of proteins. In general, globulin cells perform a protective function in the body. So far I have not encountered a single case of their erroneous or incorrect assignment. But distortion of translation always leads to inconvenience and confusion. When filling out a form for a medical report or examination, make sure that the definition of Globulin is indicated, and not the coagulation factor. This will simplify your work and save time.

What are globulins? And how do they differ from blood clotting factors? Both concepts describe blood proteins. However, globulins and factors are different terms that should not be confused with each other. In this article we will find out exactly how they differ, why they are needed and when they are used in diagnosing blood diseases. Globulins: concept and structure Globulins are macromolecules that have a protein base. They are formed through a complex biosynthetic process. Their molecular weight is 80-200 kDa. In the blood they are represented by three types of globulins or fractions (gamma, alpha and beta globulins). Antihemophilic drugs contain all types of globulin, and the ratio may differ for different versions of the drug. Thus, some drugs have a higher content of gamma globulins, which increases their effectiveness and allows them to act more strongly. For dilution, saline solution or blood is used. It is important to note that the effect on erythropoiesis with antihemophilic drugs is less pronounced, which expands the indications for their use. All types of globulin compounds consist of two fragments: a core, or rod, and an outer hydrophobic shell. The interaction of proteins with each other is carried out due to the interaction of the core of one protein with the shell of another. Depending on type