Glutaminase (Glutaminase)

Glutaminase is an enzyme that is present in the kidneys and catalyzes the breakdown of the amino acid glutamine into ammonia and glutamic acid. This reaction is one of the stages in the formation of urea in the body.

In details:

  1. Glutaminase belongs to the class of hydrolases because it catalyzes the hydrolysis reaction.

  2. The enzyme cleaves the bond between the amino group and the glutamic acid residue in the glutamine molecule.

  3. As a result, ammonia and glutamic acid are formed.

  4. This reaction occurs in the cells of the proximal tubules of the kidneys.

  5. The resulting ammonia is subsequently used to synthesize urea, which is excreted from the body in the urine.

  6. Thus, glutaminase plays an important role in the process of removing excess nitrogen from the body.

  7. Disturbances in the functioning of this enzyme can lead to pathologies in the metabolism of nitrogenous compounds.



Glutaminase is an enzyme that plays an important role in the metabolism of amino acids in the human body. It is present in the kidneys and is involved in the breakdown of the amino acid glutamine into ammonia and glutamic acid.

Glutaminase catalyzes the formation of urea, which is the main product of protein metabolism in the body. Urea is then excreted from the body through the kidneys along with other waste products.

It is important to note that glutaminase is also involved in other processes related to amino acid metabolism. For example, it may play a role in regulating glutamate levels, which is an important neurotransmitter in the central nervous system.

In general, glutaminase plays an important role in many amino acid metabolism processes in the body, and its dysfunction can lead to various diseases such as kidney failure and other metabolic disorders.

Thus, glutaminase is an important enzyme involved in various amino acid metabolism processes, and its functions are of great importance for human health.



Glutaminase is an enzyme that is involved in biochemical processes in the human body. It plays an important role in maintaining the balance of amino acids such as glutamine and glutamic acid. Glutaminase is involved in the formation of urea, which is the main breakdown product of proteins.

Glutaminase is present in the kidneys of humans and other animals. It catalyzes the breakdown of the amino acid glutamine into ammonia and glutamic acid. This process occurs in the kidneys, where glutamic acid is used to synthesize urea, the main breakdown product of proteins in the body.

However, glutaminase can also participate in other biochemical processes, such as the synthesis of proteins and amino acids. In some cases, increased glutaminase activity may be associated with various diseases such as kidney failure, diabetes, cancer and others.

Thus, glutaminase plays an important role in the human body and is involved in many biochemical processes. Its activity may be associated with both positive and negative health effects.