Gradenigo Syndrome

Gradenigo syndrome

Gradenigo syndrome is a rare neurological disease characterized by a triad of symptoms: pain in the forehead and eyes, abducens nerve palsy (VI cranial nerve) and hearing loss.

This syndrome was first described by Italian otorhinolaryngologist Giuseppe Gradenigo in 1900. The cause of this syndrome is inflammation of the maxillary sinus (sinusitis), which spreads to adjacent anatomical structures.

Main symptoms:

  1. Pain in the forehead and eye on the affected side, increasing with movement of the eyeball.

  2. Abducens nerve palsy, which results in double vision and the inability to move the eyeball outward.

  3. Hearing loss due to damage to the auditory nerve.

  4. Headache worsens when bending over and coughing.

For diagnosis, CT or MRI of the brain is used. Treatment includes antibiotics, sinus drainage and, in severe cases, surgery. With timely treatment, the prognosis is favorable.



Gradenigo syndrome, or swelling of the tonsils, is a disease of the respiratory tract, which is accompanied by enlargement of the tonsils and the formation of a throat abscess. It occurs in people of all ages and nationalities. This article will tell you about the causes, symptoms, diagnosis and treatment of gradenigo syndrome.

What is gradenigo syndrome? Gradenigo was an Italian physician in the 19th century who discovered and described gradenigo syndrome. Swelling of the tonsils is one of its symptoms. In recent years, the disease has become common in Western countries due to the use of antibiotics.

Causes of gradelig syndrome The main cause of gradelig syndrome is respiratory tract infections. Bacteria, viruses, or fungi can cause your tonsils to become swollen and tender. Other factors may lead to the development of grading syndrome, such as changes in the immune system, allergies to certain substances, stress, or genetic factors.

Symptoms of gradenic syndrome Swelling and tenderness can occur in different parts of the pharynx. In the initial stages of the disease, pain may be felt only on one side of the throat, and then spreads to the other side. Other symptoms may include dry mouth, loss of appetite, throat discomfort when swallowing, fever, swollen neck lymph nodes, headache and fatigue. Symptoms may worsen before bed or at night as breathing through the nose is difficult.

Diagnosis of Gradanigo Syndrome To diagnose Gradanigo Syndrome, the doctor usually examines the patient's throat. He may notice enlarged tonsils at the front or back of the throat