Hematodin

HEMATOIDIN is a yellowish-reddish solid substance that is a product of the breakdown of red blood cells (hemoglobin) from subcutaneous and retroperitoneal hemorrhages, intramuscular tumors from hematopoietic blood elements. It is most often found in blue. The term was proposed by an English dermatologist

What is hematoidin?

Hematoidin is a yellowish-brownish pigment that is a product of the breakdown of hemoglobin in the blood and accumulates inside the hematoma. Hematurin, i.e. blood enters tissue when a capillary or vessel ruptures. This pigment is usually located in the central part of the hematoma, located inside the tissues (in the cartilage tissue of the airways) or under the skin. The level of pigment at the opening of the injury increases as the disease progresses and the volume of damaged tissue increases. In this case, the level of detection of hematoidin directly depends on the color intensity of the substance. Usually, due to the dark colors of this pigment, the presence of injury is determined in patients with damage to the trachea, esophagus, etc. Hematurin is characterized by yellow-orange shades due to the presence of helolysin, a protein containing the heme molecule of bile.

Practical use of hematoidin

The use of the hematoindin test is based on the property of this substance that immediately after contact with fresh blood, the tissue acquires a red-brown color due to a pronounced reaction of hematoindins with ascorbic acid. To speed up the reaction, the method uses a chromium mixture. During the test, a dye solution is dripped onto the tissue in the desired location, after which the damaged area is examined. If a color change occurs after the solution interacts with the tissue, this indicates the presence of injury or tissue death. The color of the spot has the following interpretations: * yellow – the wound is fresh, the structure of the structure of the skin or mucous membrane has mainly been disturbed; * red – indicates a recent long-standing injury; * green – the injured area is old, with traces of tissue destruction; * black – indicates a completely destroyed area. Use of hematoidin for injuries

There is the following method for using hematoidin: after injury, to assess the duration of the damage, it is necessary to remove the dying parts of the affected cells from the surface of the epidermis/skin. This leads to an increase in the diagnostic value of the analysis. To get the necessary information, you need to check the places nearby. If the shade of the defect approximately matches the color of a bruise or abrasion, then you need to be prepared for the fact that some time later it will transform into “hematoidin” or “bruise,” depending on the degree of trauma. How to increase the information content of hematoidin studies: - good illumination of the research area should be ensured; - it is necessary to use a fluorescent dye;