Heterohemotransfusion is blood transfusion from people with a different blood type. This is done in cases where the blood of one person is not suitable for transfusion to the patient due to incompatibility of ABO or Rh antigens. Heterogeneous blood is given to a patient through transfusion only if it is the only appropriate method.
Heterohemo-transfusion is the process of transfusion of blood and its components to patients with incompatibility of factors of the ABO, Rh and MNS system, as well as during group immunoconflict transfusions. The procedure consists of matching ABO, Rh blood (recipient) with ABO from the donor in terms of ABO antigens. Donor erythrocytes are not subject to sensitization, as they are resistant to precipitation reactions.
The list of complications after transfusion: incompatible homologous components are caused by the following factors:
1. Slowly occurring, but fraught with serious consequences of blood clotting - impaired hemostasis. 2. Lymphocytic reaction to a foreign antigen, which leads to loss of blood compatibility with the immune response of the donor and recipient. 3. Blood clot formation or disseminated intravascular coagulation
Until recently, all these processes continued to develop actively. With the development of genetic technologies, methods for determining blood groups have appeared for the precise selection of certain blood types - the method of artificial chromosomes and the determination of HLA antigens. Modern medical technologies have made it possible to carry out typing of human hemagglutinating antibodies, which has increased the survival rate of the patient after the transplantation procedure, determined individual indications for anti-immune drugs and prescribed appropriate incest prevention.