**Cholangitis and uremia** are inflammatory diseases of the bile ducts and kidneys. These pathologies are characterized by the development of acute or chronic inflammation, impaired patency and outflow of bile and urine, damage to the liver and kidney parenchyma, and the addition of infection. Etiology. Intrahepatic and extrahepatic causes of the disease: violation of the diet with excess consumption of fats and carbohydrates disruption of digestive processes exposure to toxic substances, alcohol increased acidity in the stomach and gall bladder metabolic disorders (carbohydrate diseases