Hyperpolarization is the process by which the potential inside the cell becomes more negative than the potential on the outside of the membrane. This occurs when potassium and sodium ions move across the membrane into or out of the cell, respectively.
Hyperpolarization can be active or passive. Active hyperpolarization occurs when a cell generates an electrical current using the energy of ATP. Passive hyperpolarization does not require energy to occur and can be caused by various factors such as changes in ion concentration or changes in temperature.
However, in some cases, passive hyperpolarization can also be caused by the DC anode. This is called passive hyperpolarization under the anode. This phenomenon occurs when the cell membrane becomes less permeable to potassium and sodium ions, causing the potential inside the cell to increase.
This process may be useful in some situations, such as treating cardiac arrhythmias. However, if hyperpolarization continues for too long, it can lead to cell damage and other negative effects.
Overall, passive hyperpolarization under the anode is an interesting phenomenon that can be used in medicine and other fields. However, it is necessary to take into account the possible negative consequences of this process and use it only in cases where it is really necessary.
Hyperpolarizations are classified as one of the options for the formation of long-term excitability under conditions of homotypic action (normally they are carried out strictly selectively). The hyperpolarizing effect most often develops in response to changes in the functional state of neuronal mitochondria. This is due to the ability of drugs to cause increased intake