Ibusan

Country of origin UK, Sanofi Winthrop Industry UK
Pharm-Group Anti-inflammatory drugs - propionic acid derivatives

Manufacturers Sanofi (UK), Sanofi Winthrop Industry (UK)
International name Ibuprofen
Synonyms Apo-Ibuprofen, Bartel drugs ibuprofen, Bolinet, Bolinet Lingval, Bonifen, Bren, Brufen, Brufen retard, Burana, Dolgit, Dolgit cream, Ibalgin, Ibupron, Ibuprof, Ibuprofen, Ibuprofen Lannacher, Ibuprofen Nycomed, Ibuprofen-Akos, Ibuprofen- Teva, Ibuprofen-Hemo
Dosage forms: tablets 200 mg, tablets 400 mg
Composition Active substance: Ibuprofen.
Indications for use: Rheumatoid arthritis, reactive synovitis in osteoarthritis deformans, psoriatic arthritis, acute joint attack in gout, ankylosing spondylitis (Bechterew's disease), cervical spondylosis, Barre-Lieu syndrome (cervical migraine, vertebral artery syndrome), lumbodynia, sciatica, thoracic radicular syndrome, bursitis, tenosynovitis, myalgia, neuralgic amyotrophy, occipital and intercostal neuralgia, ligament sprains, hematomas, trauma, pain in the surgical wound area, toothache, oral surgery, panniculitis, tonsillitis, pharyngitis, laryngitis, sinusitis, rhinitis , bronchitis, pneumonia, inflammatory processes in the pelvis, dysalgomenorrhea, colds, ARVI, febrile states, postural hypotension when taking antihypertensive drugs, nephrotic syndrome (to reduce the severity of proteinuria).
Contraindications Hypersensitivity, peptic ulcer of the stomach and duodenum in the acute phase, nonspecific ulcerative colitis, aspirin-induced asthma, leukopenia, thrombocytopenia, hemorrhagic diathesis, severe dysfunction of the liver and kidneys, portal hypertension, arterial hypertension, heart failure, diseases of the optic nerve, scotoma , amblyopia, color vision impairment, pregnancy, breastfeeding.
Side effects: Dyspeptic disorders (nausea, heartburn, anorexia, vomiting, discomfort in the epigastric region, flatulence, diarrhea, constipation), erosive and ulcerative lesions of the gastrointestinal tract with signs of gastrointestinal bleeding, headache, dizziness, tinnitus, insomnia, agitation, visual disturbances (blurred vision, changes in color vision), fluid retention, edema, increased blood pressure, thrombocytopenia, granulocytopenia, hemolytic anemia, Quincke's edema, broncho-obstructive syndrome, allergic skin reactions.
Interaction Reduces the antihypertensive activity of ACE inhibitors, the natriuretic activity of furosemide and hypothiazide. May increase the toxicity of methotrexate and lithium preparations. When combined with coumarin-type anticoagulants and alcohol, it increases the risk of hemorrhagic complications, and with tableted glucocorticoids - the risk of gastrointestinal bleeding. It is not recommended to use simultaneously with acetylsalicylic acid or other NSAIDs, antidiabetic drugs, phenytoin and hormonal contraceptives. Increases the concentration of digoxin in plasma. Caffeine enhances the analgesic effect of ibuprofen.
Overdose Symptoms: abdominal pain, nausea, vomiting, lethargy, drowsiness, depression, headache, tinnitus, metabolic acidosis, coma, acute renal failure, hypotension, bradycardia, tachycardia, atrial fibrillation and respiratory arrest. Treatment: gastric lavage, activated carbon, forced diuresis, hemodialysis, symptomatic therapy.
Special instructions Considering the possibility of developing NSAID gastropathy