Immunodominant Antigen Groups

Immunodominant groups of an antigen are chemical groups that determine the specificity of antigenic determinants. They are key elements of the immune system and play an important role in determining the body's immune response to various antigens.

The immunodominant groups of an antigen can be different in their structure and function. These may include peptides, glycoproteins, lipids, nucleic acids and other molecules that are associated with antigenic determinants.

When an antigen enters the body, the immunodominant group of the antigen binds to receptors on the surface of lymphocytes, which leads to activation of the immune system. This can lead to the production of antibodies and other immune cells that will fight the antigen.

It is important to note that not all antigens have an immunodominant antigen group. Some antigens may be non-immunogenic or have only one type of antigenic determinant that does not bind to any of the immunodominant groups of the antigen.

Studying the immunodominant group of an antigen is an important aspect for understanding the immune response to antigens and developing new treatments for infectious diseases.

Immunodominance (immunomodulatory effect) is defined as a characteristic feature of some groups of antigens compared to others, consisting in their ability to dominate other antigenic determinants of the body. There are dominant and subdominant immunodominance. Subdominant antigens determine the specificity of the organism only in relation to host tissues that are strictly defined for each specific subdominant antigen. If we take into account that there are up to 350-400 units of subdominant antigens, and about a dozen dominant ones, it will be clear that when combining all tissue antigens there will be more than 3 thousand units of antigenic determinants.