Immunoglobulin G

Immunoglobulin G (IgG) is one of the main classes of immunoglobulins in the human body. It plays an important role in protecting the body from various infections and other pathogenic agents. Immunoglobulins G are the main antibodies produced in response to infection and help protect the body from reinfection.

IgG consists of four subunits, each of which contains two heavy and two light polypeptide chains. The heavy chains of IgG have a molecular weight of about 50 kDa, and the light chains have a molecular weight of about 25 kDa. IgG has several functions, including binding antigens, neutralizing toxic substances, and activating complement.

After infection, the body begins to produce IgG antibodies, which bind to antigens and neutralize their activity. This helps protect the body from re-infection. IgG can also be used to diagnose various diseases such as HIV, hepatitis and other infectious diseases.

In addition, IgG can be used as a therapeutic agent for certain diseases. For example, in rheumatoid arthritis, immunomodulatory drugs containing IgG antibodies can help reduce inflammation and improve joint function.

In general, IgG immunoglobulins play an important role in the human immune system and are an important component of the body's defense against infections.