Immunological Deficiency Secondary

Immunological Deficiency Secondary: Causes, Symptoms and Treatment

Secondary immunological deficiency (I.S.I.) is a condition that occurs as a result of damage to the initially unchanged immune system. Unlike primary immunodeficiency, which is caused by disturbances in the development of the immune system during prenatal development or early childhood, I.N.V. develops at a later age and is associated with various reasons.

Reasons for I.N.V.

Secondary immunological deficiency can be caused by various factors such as infections, tumors, drugs, autoimmune diseases or stress. Infections, especially chronic ones, can lead to long-term depletion of the immune system. Tumors can also suppress the immune system by producing substances that inhibit immune cells. Medicines such as immunosuppressants or chemotherapy used to treat tumors can also suppress the immune system. Autoimmune diseases, such as systemic lupus erythematosus or rheumatoid arthritis, can cause immune system dysfunction. Stress can also have a negative impact on the immune system, leading to a decrease in its functional activity.

Symptoms of I.N.V.

Symptoms of I.N.V. may vary depending on the cause and extent of the immune system disorder. Typically, patients with I.N.V. become more susceptible to infections, which may become more severe and take longer to respond to treatment. They may also experience increased sensitivity to allergic reactions and autoimmune diseases. Other symptoms of I.N.V. there may be frequent colds, fatigue, anemia, weight loss and an increasing inability to fight infections.

Treatment I.N.V.

Treatment I.N.V. may include therapy for the underlying disease that has led to a compromised immune system. Immunostimulants may also be prescribed to increase the functional activity of the immune system. In some cases, a bone marrow or tissue transplant may be needed to replace damaged immune system cells.

In conclusion, secondary immunological deficiency can occur for various reasons and lead to a decrease in the functional activity of the immune system. Early detection and treatment of the underlying disease, as well as the administration of immunostimulants, can help restore immune system function. It is important to seek help from a doctor if symptoms of I.N.V. appear in order to begin treatment as early as possible and prevent possible complications.



Secondary immunological deficiency (I.S.I.) is a condition in which a previously normally functioning immune system is weakened.

I.n.v. occurs as a result of various diseases and pathological processes that lead to damage to the immune system. Such processes include:

  1. Infectious diseases (HIV infection, measles, rubella, etc.)

  2. Malignant neoplasms

  3. Autoimmune diseases

  4. Taking immunosuppressants and immunomodulatory drugs

  5. Aging of the body

  6. Stress and exhaustion

  7. Malnutrition

When I.n.v. The production of antibodies decreases, cellular immunity is inhibited, and the functioning of phagocytes is disrupted. This leads to increased susceptibility to infections, frequent exacerbations of chronic diseases, and delayed wound healing.

Diagnostics I.n.v. includes a general and biochemical blood test, an immunogram, determination of the level of immunoglobulins and complement, and a study of the phagocytic activity of leukocytes.

Treatment is aimed at eliminating the cause of immunodeficiency. Immunomodulators, immunoreplacement therapy, and symptomatic treatment of secondary diseases are also prescribed. Regime, good nutrition, and timely vaccination are important. The prognosis depends on the nature and course of the underlying disease.