Interleukin

Interleukin is any substance from a family of proteins that control the course of hematopoiesis and immune reactions. The presence of twelve interleukins has now been established; Thus, interleukin 2 (IL-2) stimulates the formation of T-lymphocytes, so its use in the treatment of cancer is currently being studied (see Aldesleukin).



Interleukins (ILs) are a family of proteins that play important roles in the regulation of immune responses and hematopoiesis. They are key components of the cytokine network that regulates many physiological and pathological processes in the body.

Interleukins were first isolated in the 1970s, and since then more than 30 different interleukins have been identified. They are small proteins consisting of several domains that interact with receptors on the surface of cells.

One of the most well-known functions of interleukins is their participation in the regulation of immunity. They stimulate or inhibit the activity of various cell types, including T and B lymphocytes, monocytes, macrophages and other cells.

One of the most studied interleukins is interleukin-2 (IL-2). IL-2 stimulates the formation of T cells, making it an important component of the immune system. IL-2 can also be used in cancer treatment because it stimulates the body's immune response to cancer cells. However, the use of IL-2 as a therapy is limited by its high cost and potential side effects.

Other interleukins also have their own unique functions. For example, interleukin-4 (IL-4) stimulates the growth and differentiation of B cells and is involved in the formation of antibodies. Interleukin-6 (IL-6) stimulates the production of red blood cells and other blood cells. Interleukin-10 (IL-10) inhibits the activity of inflammatory cells and protects the body from infections.

The study of interleukins and their functions is important for understanding the mechanisms of the immune response and regulation of hematopoiesis. In the future, it is possible that the development of new interleukins or their combinations will contribute to more effective therapy for various diseases, such as cancer and autoimmune diseases.



Interleukin is a class of biologically active substances involved in many biological processes. Interleukins are proteins, each of which performs its own tasks in the immune system and other biological processes. There are a lot of diseases associated with dysfunction of interleukins. Unfortunately, today there is no generally accepted classification of these diseases. However, many scientists are studying certain protein compounds of the interleukin group, since each of them performs its own specific functions and is involved in the development of many pathologies and diseases.

Interleukins are often called cytokines - specific proteins, key elements in the regulation of immunity. It is on a neural basis that doctors determine the main pathological conditions of the body. Today it has become clear that specific interleukin reactions reflect the onset of all known diseases and cause the occurrence of even unusual symptoms and syndromes. Knowledge and prediction of coordinated intercellular regulatory reactions make doctors masters of the situation in the fight for the patient’s life.

Every year the number of discovered new subclasses of interleukin proteins is steadily growing and already amounts to several dozen positions. On