Intrazolin: properties, uses and side effects
Intrazolin, also known as cefazolin, is a first-generation cephalosporin antibiotic. This drug is widely used to treat infections of various origins, including respiratory tract infections, septicemia, endocarditis, osteomyelitis, wound infection, infected burns, peritonitis, urinary and biliary tract infections.
Intrazolin is manufactured by the Spanish company Torlan Laboratories and is available in powder form for the preparation of an injection solution weighing 1 g. This drug has many synonyms, including Amzolin, Ancef, Atralcef, Zolin, Zolfin, Ifizol, Kefzol, Lizolin, Natsef, Orizolin, Prozolin, Reflin, Sefazol, Totacef, Cesolin, Cefazolin and others.
Although intrazoline is an effective antibiotic, it can also cause side effects. Some can be serious and require immediate medical attention. These include nausea, vomiting, diarrhea, epigastric pain, pseudomembranous colitis, increased concentrations of liver enzymes in the blood, leukopenia, neutropenia, agranulocytosis, thrombocytopenia, lymphocytosis, hemolytic anemia, candidomycosis, allergic manifestations, including skin rashes, itching, toxic epidermal necrosis, Stevens-Johnson syndrome, erythema multiforme, angioedema, anaphylactic shock, as well as reactions at the injection site, including the formation of infiltrates and abscesses, phlebitis and thrombophlebitis.
Intrazoline may also interact with other medications. For example, probenecid may slow the excretion and promote accumulation of intrazolin. Therefore, you should consult your doctor if you are taking other medications.
Intrazolin is contraindicated in case of hypersensitivity, including to other beta-lactam antibiotics, pregnancy and breastfeeding. The simultaneous use of oral anticoagulants and diuretics, such as furosemide and ethacrynic acid, and administration to patients with severe renal impairment and gastrointestinal diseases is also not recommended. Thus, intrazolin is an effective antibiotic that is widely used to treat infections of various origins. However, like any medicine, it can cause side effects that may be serious and require immediate medical attention. Therefore, you should consult your doctor before you start taking Intrazolin and follow his instructions and recommendations.