Calcinosis Metabolic

Metabolic calcinosis: causes, symptoms and treatment

Metabolic calcification, also known as interstitial calcification, is a rare disease characterized by the accumulation of calcium in the tissues of the body. This can lead to various consequences, including tissue damage and organ dysfunction. In this article we will look at the causes, symptoms and treatments of metabolic calcification.

Causes of metabolic calcification

Metabolic calcification can be caused by various reasons, including metabolic disorders, hereditary factors, long-term use of certain medications, and other diseases. Some of the most common causes of metabolic calcification include:

1. Kidney failure: In kidney failure, the kidneys are unable to function properly and remove excess calcium from the body, causing it to accumulate in the tissues.

2. Hyperparathyroidism: This is a disease in which the thyroid gland produces excessive amounts of parathyroid hormone, which leads to increased levels of calcium in the blood and its deposition in tissues.

3. Sarcoidosis: This is a disease characterized by the formation of tumors in various organs, which can lead to disturbances in calcium metabolism.

Symptoms of metabolic calcification

Symptoms of metabolic calcification can vary and depend on which tissues of the body are affected. Some of the most common symptoms include:

1. Soreness and swelling in the area of ​​the affected tissue.

2. Restricted mobility in the affected joints.

3. Weakness and fatigue.

4. Nausea and vomiting.

5. Abdominal pain and diarrhea.

6. Breathing problems.

Treatment of metabolic calcification

Treatment for metabolic calcification depends on its cause and may include drug therapy, lifestyle changes, and surgery. For example, in case of renal failure, hemodialysis or kidney transplantation may be required, and in case of hyperparathyroidism, removal of the parathyroid gland. Treatment may also be prescribed to relieve symptoms and prevent complications.

In conclusion, metabolic calcification is a rare but serious disease that can lead to various consequences. If you suspect you have metabolic calcification, it is important to see a doctor for diagnosis and appropriate treatment. Early detection and treatment of the disease can help prevent complications and improve prognosis.

Metabolic calcification is the process of formation of calcification in tissues due to not only the deposition of calcium (coagulant component), but also the development of inflammatory processes (infiltrative, secondary component). Manifestations of diffuse interstitial liver damage are usually the syndromes of portal hypertension (ascites, portal hypertension, hyperammonemia) and hepatocellular failure (develops after surgical treatment in 50% of patients suffering from cirrhosis and who have not received maintenance therapy; in the rest, the rate of decompensation of the disease depends on the severity of cirrhosis)

Calcifications are considered a disease of advanced age, but currently there are cases of VEPC in children, as well as young and middle-aged men and women (Calcoptosis).

Extrahepatic localization of VEPC often occurs in waves and takes many years. From the moment it first appears until it is detected in the human brain, it can take from one to seven years, according to various sources. During this time, the diagnosis is not confirmed and the process continues, diagnosed as cholelithiasis. Diagnosis of calcinosis is associated with significant difficulties:

1). Clinical signs