Calcitonin

Calcitonin is a hormone produced by the parathyroid glands. It plays an important role in regulating calcium levels in the body. Calcitonin is used in medicine in the form of a drug to treat various diseases associated with bone tissue.

Calcitonin is produced in Russia and has various trade names such as Calcitrin, Miacalcic and Sibacalcin. It belongs to the pharmacological group of drugs based on parathyroid hormones.

Calcitonin is available in a standard dosage form. Its active substance is calcitonin itself. Calcitonin is used for the following indications: osteoporosis, bone pain associated with osteolysis and/or osteopenia, Paget's disease (osteitis deformans), hypercalcemia and hypercalcemic crisis, neurodystrophic diseases and acute pancreatitis.

However, there are contraindications to the use of calcitonin, such as hypersensitivity to the drug, pregnancy and breastfeeding. When using calcitonin, side effects may occur, such as nausea, vomiting, dizziness, flushing, feeling hot, chills, polyuria and allergic reactions, including anaphylactic shock.

There is no information on the interaction of calcitonin with other drugs, and data on overdose is also not provided.

When using calcitonin, caution must be exercised in patients prone to allergic reactions, especially considering the peptide structure of the drug. It is recommended to simultaneously ensure a sufficient supply of calcium and, possibly, vitamin D in the patient's body during the treatment of osteoporosis, taking into account individual needs.

Calcitonin may significantly reduce serum alkaline phosphatase activity and reduce urinary hydroxyproline excretion in Paget's disease and other chronic conditions characterized by increased bone turnover. However, sometimes the values ​​of these indicators may increase after an initial decrease, and in such cases, temporary cessation of treatment may be necessary. Disorders of bone metabolism may recur after one or several months, so a second course of treatment may be required.

Caution is advised when administering calcitonin. Please note that I cannot provide information on specific brand names and drug availability in specific countries or regions as this information may change over time and may vary from location to location. To obtain up-to-date information about specific drugs and their availability, it is better to contact a medical specialist or search for information on the websites of official medical organizations or pharmaceutical companies.

Calcitonin is one of the most important hormones in the human body, which regulates the level of calcium in the blood and tissues. It is produced in the thyroid gland and is an inhibitor of other hormones such as parathyroid hormone and parathyroid hormone, which regulate calcium levels in the body.

Calcitonin may also influence other processes such as bone growth and development, muscle activity, and fat metabolism. When calcium levels in the blood are low, calcitonin levels increase, which helps lower calcium levels in the blood.

With increased levels of calcitonin in the blood, calcium can accumulate in soft tissues, which can lead to the development of various diseases, such as osteoporosis, thyroid cancer and others. Therefore, controlling calcitonin levels is an important aspect in the treatment of diseases associated with calcium metabolism disorders.

However, in practice, measuring calcitonin levels is not a routine test because it does not have high specificity and sensitivity. In addition, calcitonin levels may vary depending on age, gender, lifestyle and other factors.

Thus, although calcitonin plays an important role in regulating calcium levels in the body, its determination is not accurate and informative in the diagnosis of diseases associated with calcium levels.