Captopril-N.s.

Captopril-NS: description, application and side effects

Captopril-N.S. is an antihypertensive drug and angiotensin-converting enzyme inhibitor produced by the Russian Shchelkovo Vitamin Plant. The active ingredient of the drug, captopril, is in the dosage form of tablets, which are produced in dosages of 25 mg and 50 mg.

Captopril-N.S. used for the treatment of arterial hypertension, congestive heart failure, cardiomyopathy, left ventricular dysfunction in a stable condition in patients after myocardial infarction, diabetic nephropathy against the background of type 1 diabetes mellitus.

Like any other medicine, Captopril-NS. has some contraindications and restrictions for use. Contraindications include hypersensitivity to the drug, the presence of anamnestic information about the development of Quincke's edema with previous prescription of ACE inhibitors, hereditary or idiopathic Quincke's edema, primary hyperaldosteronism, pregnancy, and breastfeeding. Restrictions on use may be associated with an assessment of the risk-benefit ratio in cases of leukopenia, thrombocytopenia, aortic stenosis or other obstructive changes that impede the outflow of blood from the heart, hypertrophic cardiomyopathy with low cardiac output, severe renal dysfunction, bilateral renal artery stenosis or stenosis artery of a single kidney, the presence of a transplanted kidney, hyperkalemia or childhood.

Side effects that may occur with the use of Captopril-NS include fatigue, dizziness, headache, central nervous system depression, drowsiness, confusion, depression, ataxia, convulsions, numbness or tingling sensation in the extremities, visual disturbances and/or sense of smell. From the cardiovascular system and blood, hypotension, orthostatic hypotension, angina pectoris, myocardial infarction, cardiac arrhythmia, palpitations, acute cerebrovascular accident, peripheral edema, lymphadenopathy, anemia, chest pain, pulmonary embolism, neutropenia, agranulocytosis and thrombocytopenia. Parts of the digestive system may include nausea, vomiting, diarrhea, constipation, dyspepsia, increased activity of liver enzymes, and pancreatitis. Skin reactions such as urticaria, pruritus, rash, angioedema, photosensitivity, alopecia and dermatitis may also occur.

Before starting treatment Captopril-N.S. it is necessary to conduct a detailed examination of the patient, determine the presence of contraindications and restrictions for use, and also select the optimal dosage. During the treatment period, it is necessary to monitor the patient's condition and, if side effects occur, immediately consult a doctor.