Captopril Of

Captopril OF: use, contraindications and side effects

Captopril OF (international name - captopril) is an antihypertensive drug from the group of angiotensin-converting enzyme inhibitors. This drug is manufactured in Germany by Ostpharm Arzneumittel GmbH and Co. and is used to treat arterial hypertension, congestive heart failure, cardiomyopathy, left ventricular dysfunction in a stable condition in patients after myocardial infarction and diabetic nephropathy due to type 1 diabetes mellitus.

Captopril OF is available in the form of tablets containing 12.5 mg, 25 mg and 50 mg of the active substance - captopril. Captopril OF is a drug contraindicated in case of hypersensitivity, the presence of anamnestic information about the development of Quincke's edema with previous prescription of ACE inhibitors, hereditary or idiopathic Quincke's edema, primary hyperaldosteronism, pregnancy and breastfeeding. In addition, the use of captopril requires an assessment of the risk-benefit ratio in the case of leukopenia, thrombocytopenia, aortic stenosis or other obstructive changes that impede the outflow of blood from the heart, hypertrophic cardiomyopathy with low cardiac output, severe renal dysfunction, bilateral renal artery stenosis or single artery stenosis kidney, the presence of a transplanted kidney, hyperkalemia and childhood.

Captopril OF may cause various side effects. From the nervous system and sensory organs, fatigue, dizziness, headache, central nervous system depression, drowsiness, confusion, depression, ataxia, convulsions, numbness or tingling sensation in the extremities, visual and/or smell disturbances may be observed. From the cardiovascular system and blood (hematopoiesis, hemostasis), hypotension may occur, including orthostatic, angina pectoris, myocardial infarction, cardiac arrhythmia (atrial tachy- or bradycardia, atrial fibrillation), palpitations, acute cerebrovascular accident, peripheral edema , lymphadenopathy, anemia, chest pain, thromboembolism and/or hypokalemia. Digestive system disorders such as nausea, vomiting, diarrhea, abdominal pain, increased liver function tests, angioedema, urticaria, itching and other allergic reactions may also occur.

If side effects occur, you should consult your doctor, who can decide whether to continue using captopril or change it to another drug. It is also necessary to follow dosage recommendations and not exceed the recommended dose to avoid possible negative consequences.

In general, captopril OF is an effective and safe drug for the treatment of arterial hypertension and other diseases of the cardiovascular system, provided that the doctor’s recommendations are followed and possible side effects are monitored.