Ketamine Hydrochloride

and Bryntsalov (Russia), J.R. Sharma Overseas (India), Moscow Endocrine Plant (Russia), Temis Chemicals Ltd (India), Ferein (Russia), Chemo Iberica (Spain)

Ketamine, also known under the synonyms Calipsol, Ketalar and Ketanest, is a non-inhaled narcotic drug from the group of non-barbiturates. The active ingredient of the drug, ketamine, has anesthetic properties and is widely used in medicine for pain relief during short-term operations and painful instrumental interventions, including dental, ophthalmological, otorhinolaryngological, gynecological and obstetric practice, as well as diagnostic procedures such as endoscopy and cardiac catheterization.

Ketamine hydrochloride is produced by several pharmaceutical companies in different countries, including Russia, India and Spain. The drug is available in the form of a substance, as well as in the form of an injection solution of various concentrations.

Although ketamine is an effective agent for pain relief and anesthesia, it has some contraindications and limitations for use. For example, the drug may be dangerous for patients with cerebrovascular accidents, arterial hypertension, preeclampsia, eclampsia, alcoholism or epilepsy in children. Caution should also be exercised when prescribing ketamine to patients with kidney disease, angina, decompensated heart failure, or undergoing laryngeal or pharyngeal surgery.

Like any other medication, ketamine can cause side effects. Some of these include increased blood pressure, tachycardia, drooling, nausea, shortness of breath, respiratory depression, muscle rigidity and increased muscle activity, as well as obstruction of the upper respiratory tract due to spasm of the masticatory muscles and retraction of the tongue. When recovering from a state of anesthesia, hallucinations, psychomotor agitation, prolonged disorientation, and psychosis may be observed. In addition, ketamine may cause pain and erythema at the injection site.

It is important to consider the possibility of ketamine interacting with other medications. For example, ketamine can enhance the effects of inhalational drugs, sedatives, and alcohol, which can lead to serious complications. You should also be careful when using ketamine concomitantly with antidepressants, antipsychotics, anticonvulsants and some other drugs, as this may lead to unwanted interactions and increased side effects.

In general, the use of ketamine should only be carried out under the supervision and prescription of a physician in accordance with the indications and contraindications, as well as taking into account possible risks and side effects.