Giant Cell

A Giant Cell is any large cell, such as a megakaryocyte. Giant cells can have one or several nuclei.

Giant cells are significantly larger than normal cells. Their diameter can reach 100-150 microns. For comparison: the diameter of a red blood cell is 7-8 microns, and the diameter of a regular cell is 10-30 microns.

The presence of several nuclei is a distinctive feature of giant cells. This occurs as a result of the fusion of the precursors of these cells, each of which contributes its own nucleus to the giant cell. The number of cores can vary from several to hundreds.

Giant cells are found in humans and animals. These include osteoclasts, which are involved in bone resorption, megakaryocytes, which produce platelets, syncytiotrophoblasts in the placenta, and others.

The formation of giant cells is an important process in the immune system. They help fight pathogens and remove foreign particles from the body. Some giant cells are associated with pathological processes, such as tuberculosis.

Thus, giant cells play an important role in the body due to their unique size and multinucleate structure. Their study is important for understanding many biological processes in health and disease.

Giant Cell: Dimensions, Structure and Functions

A giant cell, also known as a giant cell, is a special form of cell characterized by an unusually large size. It can have one or several nuclei, which distinguishes it from typical unicellular organisms and most cells of multicellular organisms. Giant cells can be found in various tissues and organs, performing a variety of functions.

One example of a giant cell is the megakaryocyte, a cell that plays an important role in the formation of platelets, which are responsible for blood clotting. Megakaryocytes live in the bone marrow and have the unique ability to fuse with each other, forming giant cells with several nuclei. This process, called megakaryopoiesis, is an important step in platelet formation.

The structure of a giant cell can vary significantly depending on its type and function. They usually have a more branched structure, which ensures efficient fusion with other cells and the formation of multinuclear structures. Giant cells may also contain more cytoplasm and more developed organelles to support their specific functions.

The functions of giant cells can be varied and depend on their location in the body. For example, megakaryocytes play a role in the formation of platelets, which play an important role in blood clotting and wound healing. Giant cells may also be associated with the body's immune response to infection or inflammation. They may participate in the formation of multinucleated giant cells of inflammatory origin, such as Lanhans cells in the lungs or multinucleated giant cells in bone tissue.

In addition to their physiological functions, giant cells are also of interest to researchers and medical professionals. The study of giant cells can expand our understanding of various pathological conditions such as tumors, inflammatory diseases and circulatory disorders. They may also serve as targets for new drugs and therapeutic approaches.

In conclusion, a giant cell, whether a megakaryocyte or another type, is a special form of cell with an unusually large size. It can have one or more nuclei and perform a variety of functions related to platelet formation, immune response and other processes in the body. The study of giant cells is important for understanding various pathological conditions and developing new therapeutic approaches.

A giant cell is a large (in size or volume of cytoplasm) cell of animals and plants. “Megakaryocytes” (giant forms of red blood cells with a large nucleus combined with small ones). The giant cell is found in various multicellular tissues. For example, giant salivary, skin and muscle cells are known. May have one or more nuclei (see Multicentricity).

The cells form histiocytes, which have an ultramicroscopic branched structure. This confirms the tropism of lysosomes to the surface areas of cells. Through specific receptors, macrophage monocytes actively phagocytose microbes and their own modified cells; due to phagocytosis, the specific reactivity of the body is increased to unnatural limits, which is revealed during the “dumping” reaction as a result of blastocytosis. Normally, in humans, the maturation of monocytopoiesis follows the path of proliferation of premonocytes. If proliferation does not stop further, this leads to myeloma degeneration of cells in which abnormal proteins accumulate. The disease cells become malignant and become plasma cells. The latter, in the process of its replication, will constantly release a huge amount of primary and secondary immunoglobulins from the blood serum outside the maternal microenvironment. In pathology, we mean autoimmune aggression. The component produced during the disease is a pathological autoantibody, an attack