Crash Syndrome. Toxicosis Traumatic (Crush Syndrome)

Crash syndrome is a renal failure that develops as a result of extensive trauma and necrosis of muscle tissue.

This syndrome develops due to acute necrosis of the renal tubules, which is accompanied by the presence of myohemoglobin in the blood. Myohemoglobin is released from damaged muscle tissue.

Thus, crash syndrome is a complication that occurs when the muscles of the limbs are compressed for several hours (for example, due to rubble in buildings). This leads to the destruction of muscle cells and the release of toxic substances into the bloodstream, which causes acute renal failure.

Crash syndrome or traumatic toxicosis is a kidney failure that can occur as a result of extensive trauma that causes the destruction of muscle tissue and, as a result, the release of myoglobin cells from it into the blood. The scientific name for this disease is Crush Syndrome. This pathology often occurs when compressed by various types of injuries, bruises, severe bone fractures, dislocations of large joints. Crash syndrome can also occur for a less significant reason - for example, after a very long immobilization of the joints with a plaster cast. Typically, Crash syndrome is diagnosed on the second or third day after an emergency, although the disease can manifest itself later. As you know, in the first hours and days the victim must be provided with active non-medical medical care, eliminating the root cause and symptoms of the pathology, but then the diagnosis is established in any case. Crash syndrome differs from other injuries in that damage to the white muscles can lead to a crisis complication - poisoning of the body with its own tissues: cytostatic substances, which is characterized by systemic intoxication. This is why the disease is sometimes called “muscle breakdown syndrome.”