Ксантоматоз (Xanthomatosis)

Xanthomas (xanthomatoses) are formations on the skin that can be caused by various reasons, including hereditary diseases, endocrine disorders, metabolic disorders and other reasons. Xanthomata usually appear as soft, yellow, flat or slightly raised growths on the skin. They can occur anywhere on the body, but are most common on the face, arms, legs and back.

Xanthomas can come in a variety of sizes and shapes, and they can be either single or multiple. Some types of xanthomas may be associated with certain diseases, such as Hantaman-Pearson syndrome or Menke syndrome.

Although xanthomas are not a health hazard, they can cause psychological distress and lead to social isolation. Some cases of xanthomatosis may require treatment, such as diet or medication.

Overall, xanthoma is a condition that requires attention and treatment, so it is important to see a doctor if any skin lesions appear.

Xanthomas (xanthoma plaques) are a disordered collection of fat cells that form a whitish “sebum” or “cheese-like” appearance. The mucous membranes may also be affected. This diagnosis is made by the observer; there is usually a family history and suspicion of hypercholesterolemia. Because xanthomas are often associated with hypolipidemia, lipid profiling is recommended for patients.

Synonyms: xanthoma, xanthoma, X-spot, xanthomas of the face and limbs (international nonproprietary name), Janige's plaque. Occasionally, the term “xanthoma” is used in a broader sense, denoting something common to a group of diseases (xanthogranulomatous lichenixoid alopecia, Hurler’s disease).