Curare-Like Remedies

Curare-Like Remedies: Features of Use and Application

Curare-like drugs, also known as peripherally acting muscle relaxants or curare-like agents, are an important class of drugs used medically to relieve muscle tension and certain medical procedures. In this article we will look at the features of the use and application of curare-like remedies.

Curare-like drugs got their name due to their similarity in action to curare, a poison used by South American Indians for hunting. They block the transmission of nerve impulses to the muscles, causing them to relax and reducing muscle tension. Curare-like drugs can be used to relieve muscle spasms, cramps and pain, as well as for surgical procedures if muscle relaxation is required.

There are two main types of curare-like agents: depolarizing and non-depolarizing. Depolarizing muscle relaxants, such as succinylcholine, work by stimulating nerve receptors more intensely, resulting in a faster onset of muscle relaxation. Non-depolarizing muscle relaxants, such as atracurium, work by blocking acetylcholine receptors on muscle cells, resulting in a slower onset of muscle relaxation.

It is important to note that curare-like drugs can cause a number of side effects. For example, they can cause a decrease in blood pressure, which can lead to hypotension. Breathing problems may also occur, especially when using depolarizing muscle relaxants, which can cause paralysis of the respiratory muscles. In addition, curare-like drugs may cause allergic reactions in some patients.

The use of curare-like drugs should only be carried out under the supervision of qualified medical personnel. Dosage and route of administration must be strictly controlled to minimize the risk of side effects and ensure optimal treatment.

In conclusion, curare-like drugs are an important class of drugs used to relieve muscle spasms, medical procedures, and surgery. However, they may be associated with certain risks and side effects and their use should only be done under the supervision of qualified medical personnel. Patients prescribed curare-like drugs should be closely monitored for any changes in their condition, and measures should be taken to prevent possible complications.

In general, curare-like agents represent an important tool for the management of muscle tension and medical procedures. However, their use should be limited to only when necessary and should only be done under the supervision of qualified medical personnel.

**Curare-like** drugs are drugs that are used to relieve muscle tension. They have a **muscle relaxant** or **spasmolytic effect**. These drugs are administered intravenously or intramuscularly, and are also used as inhalations to quickly and effectively calm the patient.

Myorelaxation is the process of relieving tension in muscles that are in good shape. The curare-like effect is used both by medical professionals in the treatment process and in sports. For example, athletes can use these drugs during heavy training and competition to avoid injury and get the most out of their training.

Among the quarare-like drugs, several groups are distinguished:

**1. Tetanus toxins**, which are obtained from the causative agent of tetanus - C. tetani. These toxins are protein compounds that cause skeletal muscle relaxation. Tetanus is a dangerous disease characterized by progressive spasm and tension of the body's muscles, which can lead to serious complications including respiratory arrest and death. Antitoxic therapy includes the administration of tetanus toxoid, which produces immunity to the disease. Tetanus therapy is necessary for patients with serious injuries and illnesses caused by the bacterium C. tetani and for some patients who have neurological reactions to other bacteria or viruses.

**2. Succinylcholine**, also called “succinyl” and “afrederm”. Succinyl chloride is a chemical compound that is inactive and is used to provide anesthesia for surgical procedures. However, in therapeutic doses, under the influence of silconylcolchloride, a complete cessation of the nervous system occurs. This causes paralysis of the respiratory system, heart and muscles. This drug is also used for eye surgery through liporesection. All toxicity of this drug is due to the rapid accumulation of metabolites in the blood.

Drugs based on the substance paralyze the respiratory system, diaphragm, bronchi, and relieve tension in the intestines and urinary tract. The therapeutic effect is ensured by the rapid expansion of blood vessels and the absence of a reflex effect causing vasoconstriction. In case of overdose, the drugs cause the death of a patient with cardiac disorders, severe