Langerhans Cell

Langerhans cell: Role in the immune system

The Langerhans cell (also known as the Langerhans dendritic cell) was first described in 1868 by the German pathologist Paul Langerhans. These cells are found in the epithelium of the skin, mucous membranes and other tissues, where they play an important role in the immune system.

The Langerhans cell is a key element of the immune system as it is an efficient antigen-presenting cell type. They can capture and process antigens, which are then presented to immune cells such as T cells and B cells. This process is called antigen presentation.

In addition, Langerhans cells also play an important role in immune system tolerance. They can induce tolerance to antigens found on tissues such as skin to prevent an immune response to the body's own tissues. This process is called immune tolerance.

Despite the fact that Langerhans cells are found in different tissues, they have a common structure. They have a dendrite-like shape, with long and thin projections that allow them to communicate with other cells in the immune system.

The study of Langerhans cells is of great importance for understanding the immune system and its functions. For example, recent studies have shown that Langerhans cells may play an important role in the development of allergic reactions and the immune response in autoimmune diseases.

In conclusion, Langerhans cells are an important component of the immune system that plays an important role in antigen presentation and immune tolerance. Studying these cells is of great importance for understanding the immune system and developing new treatments for immune diseases.

Langerhansa Janus (Latin - cellular element) - pathologically altered cells on behalf of Johann Langerhanz (German anatomist, pathologist), who for the first time discovered the appearance of abnormal cellular elements on cholera contaminated soils due to the penetration of a pathogenic microbe. An elementary leukemia cell is formed from lymphocytes (erythroblastoid elements). Langersantia to infectious diseases has a certain significance, but when microbes are introduced, it does not completely coincide with the morphological sign of their disease. In some people, this cell may appear during decay in the kidney, qi