Dosage Form Parenteral

There are two different opinions about the dosage form “parenteral” or “parenteral”. Some doctors believe that it can only be used when it is necessary to introduce certain drugs into the body by injection into the blood, while others believe that parentoral drugs can be introduced into the body in other ways, for example, in the form of solutions taken by mouth or inhalers.

However, there are earlier opinions of doctors on this topic. They believed that parenteral drugs were liquid or semi-liquid formulations that could be administered into a person's bloodstream through a catheter or other medical devices. This method of administration involves the use of special containers that are part of a parenteral set, also called an “infusion bag”.

In general, when we think of parenteral administration, we usually think of liquid drugs administered directly into the patient's bloodstream, however, in some cases this may even be an oral or rectal route of administration. For example, vitamins can be administered in a specific way to ensure complete absorption by the body.

Thus, although not everyone agrees, it is believed that the term "parenteral" can be used to refer to drugs used for injection into the human body, or that are introduced into the body through other means, such as inhalation.

Parenteral dosage forms are dosage forms that are introduced into the body through blood vessels (venous or intravenous). These forms include solutions, suspensions and emulsions, which are intended for intravenous or subcutaneous administration.

Parenteral forms are usually used to rapidly introduce a drug into the blood to ensure rapid action of the drug and avoid the effects of systemic absorption, such as the effects of absorption through the gastric or intestinal mucosa. They can be used to quickly deliver a drug to an organ or system to achieve a quick effect. However, these forms have their limitations, such as risks of systemic toxicity, dosing errors, risk of allergic reactions, and the potential risk of local reactions at the site of administration, such as infections and hematomas. In addition to medical indications, injections are used in cosmetic surgery, fitness and sports to reduce body fat. In these cases, drugs are injected deep into the skin to enhance thermogenesis. However, there are also side effects when the medicine causes the development of local inflammation, increased skin sensitivity and the development of infection. Non-steroidal anti-inflammatory drugs are especially dangerous, the use of which leads to scarring. Injections can also be included in therapeutic and preventive protocols for the treatment of dermatological diseases: eczema, psoriasis, acne, rosacea, seborrheic dermatitis. In this case, injections are carried out into the upper layers of the epidermis or the epidermal-dermal layer. Along with medications, hyaluronidase is injected into the affected area, which allows you to prolong the therapeutic effect of the main drug - hydrocortisone. When it comes to cosmetic procedures, the goal is most often to improve the appearance of the skin. This means that in order to preserve youth, beauty and health, it is necessary to compensate for the loss of useful elements or strengthen the immune system. The most commonly used injections are collagen solution, hyaluronic acid, and liquid silicone.

Dosage form Parenteral is a method of introducing a drug into the body through the blood or lymph, bypassing the digestive tract. It is used to quickly and effectively achieve the maximum concentration of a drug in the body and its access to tissues and organs. It is used when a quick response to a change in the body’s condition is necessary, for example, during emergencies, after surgery, or in the presence of breathing problems. Parenteral dosage forms include injections, infusions, transfusions, and plateletpheresis.

Advantages of parenteral administration:

- rapid achievement of maximum concentration - high efficiency - the possibility of direct access of the drug to the diseased organ - the digestive system is not affected

Flaws:

– pain factor when giving an injection - risk of damage