Macrolides are a group of antibiotics that are produced by actinomycetes (microorganisms similar to bacteria) and have a macrocyclic lactone ring in their chemical structure (a lactone is a cyclic compound that is formed when a water molecule is split off from an acid molecule). Aminosaccharide residues may also be associated with a lactone ring.
Macrolides have a broad spectrum of antimicrobial activity and can be used to treat infections caused by various types of bacteria. They are especially effective against gram-positive bacteria such as staphylococci, streptococci and pneumococci.
One of the most famous representatives of macrolides is erythromycin. It was discovered in 1952 and is still used today as a broad-spectrum antibiotic. Erythromycin is active against many gram-positive and gram-negative bacteria, including gonococci and meningococci. It is also effective against some anaerobic bacteria.
However, like all antibiotics, macrolides have their side effects and contraindications. They can cause allergic reactions, diarrhea, nausea and other gastrointestinal disorders. Additionally, they may interact with other medications, which may cause unwanted effects. Therefore, before starting treatment with macrolides, you should consult your doctor and follow his recommendations.
Macrolide antibiotics are a group of antibiotics that are an indispensable component in medical practice. These drugs are very important for treating various diseases caused by bacteria. They can be used to treat infections of the lungs, digestive organs, skin, etc. One type of such drugs is macrolide antibiotics. What is it