Mefoxin

Mefoxin, a broad-spectrum antimicrobial drug from the cephalosporin group. Its chemical structure is similar to penicillins and has a bactericidal effect.

The mechanism of action is due to inhibition of the synthesis of murein-binding peptide in the cell walls of microorganisms and stabilization of the membrane structures of bacterial cells.

Active against gram-positive and gram-negative bacteria, such as Esherichia coli, Proteus spp., Klebsiella spp., Haemophilus influenzae, Neisseria catarralis, Staphylococcus spp. (including Staphylococcus aureus, penicillinase-producing and non-penicillinase-producing strains), Neisseria meningitidis, Shigella spp., Salmonella spp. Cephalosporins should be prescribed with caution if there is a history of allergies to penicillin and allergic diathesis. Therapy should be adjusted based on the results of antibiotic sensitivity testing if the classic pattern of infections involving drug-sensitive microorganisms is absent or the patient’s condition does not improve. Mefoxia should not be used in case of hypersensitivity and increased tendency to bleeding after the use of other cephalosporin antibiotics. In some cases, cross-resistance occurs. May increase the side effects of other drugs that cause photosensitivity or bleeding disorders when administered together.