Myasthenic Reaction

Myasthenia gravis (Milgren's disease) is a rare neuromuscular disease. It manifests itself as muscle weakness, impaired coordination of movements, and difficulties in pronouncing words. When the disease occurs, the muscles contract with greater delay, and gradually it becomes difficult to even just get out of bed, not to mention normal activity.

Pathology can be inherited and acquired, develop



Myasthenic reaction: understanding and clinical significance

Myasthenic reaction, also known as Jolly's syndrome, is a neurological condition characterized by weakness and rapid fatigue of skeletal muscles. The term "myasthenia" comes from the Greek words "mia" (muscle) and "asthenia" (weakness), which emphasizes the main symptoms of this condition.

The manifestation of myasthenic reaction is usually associated with increased muscle activity or increased physical stress. Patients suffering from this condition may experience weakness and fatigue even when performing simple daily tasks such as climbing stairs or lifting heavy objects. Symptoms may worsen over time and lead to significant limitations in patients' daily lives.

The mechanism underlying the myasthenic reaction is associated with impaired transmission of neuromuscular impulses to the motor limbs. This is caused by autoimmune disorders in which antibodies are directed against acetylcholine receptors, which are responsible for transmitting nerve impulses to muscles. As a result, the number of functioning receptors decreases, which leads to impaired muscle contraction and symptoms of weakness.

The diagnosis of myasthenic reaction is usually based on clinical assessment of symptoms, monitoring the response to pharmacological agents such as pyrostigmine or neostigmine, and performing electromyography to assess the electrical activity of the muscles. It is important to note that myasthenic reaction can be a symptom of other more serious conditions, such as myasthenia gravis or brain tumors, so further testing may be needed to rule out these conditions.

Treatment of myasthenic reaction is aimed at relieving symptoms and improving the quality of life of patients. The main method of treatment is the use of anticholinesterase drugs, which increase the concentration of acetylcholine in the synaptic cleft and improve the transmission of nerve impulses to muscles. In some cases, immunomodulatory drugs or corticosteroids may be prescribed to reduce inflammation and suppress the immune system.

In conclusion, myasthenic reaction is a neurological condition characterized by muscle weakness and fatigue. It is caused by impaired transmission of neuromuscular impulses and autoimmune disorders. Diagnosis is based on clinical assessment of symptoms and additional testing. Treatment is aimed at relieving symptoms and may include anticholinesterase drugs and other medications.

However, it is important to note that this article is not a substitute for consultation with a medical professional. If you suspect myasthenic reaction or any other medical condition, consult your doctor for professional medical advice and diagnosis.