Microcytosis

Microcytosis is the presence of abnormally small red blood cells (microcytes) in the blood.

Microcytosis is a characteristic feature of some anemias (microcytic anemias), including iron deficiency anemias; a number of hemoglobinopathies; anemia arising from various chronic infectious diseases, etc.

In microcytosis, red blood cells have a smaller than normal mean volume (MCV or mean cell volume). This is due to a violation of hemoglobin synthesis and a decrease in its content in red blood cells.

The main reasons for the development of microcytosis:

  1. Iron deficiency, which interferes with hemoglobin synthesis. This is the most common reason.

  2. Disorders of hemoglobin synthesis in thalassemia and other hemoglobinopathies.

  3. Chronic diseases (infections, inflammations) leading to impaired iron metabolism.

  4. Intoxication with lead, tin and other heavy metals.

Diagnosis of microcytosis is based on a blood picture analysis with calculation of indices (MCV, MCH, MCHC). Additional research may be required to determine the cause and treatment options.



Microcytosis is a medical term that describes the presence of abnormally small red blood cells, also known as microcytes, in the blood. This phenomenon may be a characteristic feature of various anemias, including microcytic anemias, hemoglobinopathies, and anemias associated with chronic infections.

Microcytosis means that the red blood cells in the blood are smaller than normal size. Normally, healthy red blood cells measure 6 to 8 micrometers in diameter. With microcytosis, the size of red blood cells can be less than 6 micrometers. This can lead to the fact that red blood cells cannot perform their main function - delivering oxygen to the tissues and organs of the body.

Microcytosis is one of the most common signs of iron deficiency anemia, which occurs when there is a lack of iron in the body. Iron is necessary for the formation of hemoglobin, a protein that binds oxygen in red blood cells. With iron deficiency, the amount of hemoglobin decreases, which can lead to microcytosis.

In addition, microcytosis can be a sign of a number of hemoglobinopathies - hereditary diseases associated with changes in the structure of hemoglobin. Some forms of hemoglobinopathies, such as beta thalassemia and hemoglobin C, can lead to microcytosis.

Microcytosis may also be associated with various chronic infectious diseases such as human immunodeficiency virus (HIV) infection, viral hepatitis, tuberculosis and others.

Diagnosis of microcytosis is carried out using a blood test, which allows you to determine the size of red blood cells and the amount of hemoglobin. Treatment for microcytosis depends on the underlying disease that caused it. In the case of iron deficiency anemia, patients may be prescribed iron supplements to correct the deficiency, and in the case of hemoglobinopathies, blood transfusions may be required.

In conclusion, microcytosis is a characteristic feature of various diseases associated with impaired formation and functioning of red blood cells. Diagnosis and treatment of microcytosis should be carried out under the supervision of a physician to achieve the best treatment result and prevent possible complications.



Microcytosis is the presence of abnormally small red blood cells in the blood.

Microcytosis may be one of the signs of some anemias. It may be due to iron deficiency in the body, as well as a number of other reasons, such as hereditary factors, genetic abnormalities and some infectious diseases.

Anemias that are characterized by microcytosis include iron deficiency anemias, hemoglobinopathies, and anemias of chronic infectious diseases.

Hemoglobinopathies are a group of diseases with