Myeloblast

Myeloblasts are undifferentiated cells of the myeloid lineage that are the precursors of granulocytes and monocytes. Myeloid cells play an important role in the immune system, participating in the body's defense against infections and other pathogens.

Myeloblasts are formed in the bone marrow, where they undergo the process of differentiation into mature myelocytes, which then migrate to the peripheral blood, where they perform their functions. Normally, myeloblasts make up less than 1% of all bone marrow cells. However, in some diseases, such as acute myeloid leukemia, the number of myeloblasts can increase significantly, leading to the development of myeloproliferative syndrome.

One of the main functions of myeloblasts is the production of interleukins and other cytokines that regulate the body's immune response. In addition, myeloblasts participate in the process of phagocytosis, that is, the absorption and destruction of bacteria and other foreign particles.

However, myeloid cells can also become cancerous and lead to the development of acute myeloid leukemia. With this type of leukemia, myeloblasts begin to divide uncontrollably and spread throughout the body, which can lead to serious complications and even death of the patient.

Various methods are used to diagnose myeloid leukemia, such as cytogenetic studies, immunophenotyping and molecular genetic tests. Treatment for myeloid cells may include chemotherapy, radiation therapy, and bone marrow transplantation from a healthy donor.

In general, myeloblastic leukemia is a serious disease that requires timely diagnosis and treatment.

Myeloblasts are a neoplastic cell and a cellular and neoplastic species of the "leukopoiesis" family. Cell growth factors stimulate the differentiation of blast cells into myeloblasts. Blast cells can be distinguished from normal immature and mature erythroid cells by