Neuroxanthoma

Neuroxanthomas are neoplastic lesions of the skin (histological forms of benign acanthotinia), resulting from hyperplasia and death of epidermal cells with the formation of thick yellow-brown layers of keratin and melanin, in which many capillary vessels are observed. This case examines cases of neuroxanthoma in several patients **General information:** neuroxanthoma is also called neurokeratoma, neurokeratofibroma. It develops in stages. As a result of increased melanin production, the number of peroxides sharply increases, melanins damage the basement membrane of keratinocytes, atrophy, vacuolization and apoptosis are noted. The result of this stimulation may be neoplasia or mutation of normal cells in the intermediate layer of the epidermis - the marginal zone of the hair follicle. These cells grow and form new growths of an unnatural color and consistency, often pinkish or grayish-pinkish in color. The neoplastic process spreads through specialized cells of the epidermis and can affect the dermis, muscles, and bones. Neuroxanthoma begins to actively grow, the skin turns red and pain appears. Skin formation of different sizes occurs, which appears against the background of previous active insolation on poorly healed traumatic injuries to the skin. If such rashes develop only after prolonged exposure to the sun, this is a symptom of Dubois neurofibromatosis. In such a condition as neurofibromas, it is necessary to carry out careful dynamic monitoring and prevention of the tumor process, because genetic predisposition is the trigger for the development of the disease. The most important thing is to remove lesions correctly.

According to recent studies, a very important aspect is the age and gender of the patient. Also, such rashes almost never occur in children; they are of mature age and during development are at risk of developing a fungal infection, which usually always accompanies the formation of neurofibromas. Against the background of the development of neurofibros, one should