Neostigmine (Neostigmine)

Neostigmine is a parasympathomimetic drug that inhibits the action of the enzyme cholinesterase (see also Anticholinesterase). It is used primarily for the diagnosis and treatment of myasthenia gravis, and also as an antidote to certain drugs - muscle relaxants (for example, tubocurarine). It is also used to treat certain intestinal diseases and glaucoma. Neostigmine can be given orally, by injection, or as eye drops; Possible side effects: digestive disorders and increased salivation. Trade name: Prostigmin.

Neostigmine is a medicinal substance that is used to treat various diseases associated with dysfunction of the nervous system. The main mechanism of action of neostigmine is the inhibition of the action of the enzyme cholinesterase, which destroys the neurotransmitter acetylcholine. This leads to an increase in the concentration of acetylcholine at the synaptic endings of nerve fibers, which improves the transmission of nerve impulses.

The use of neostigmine is widespread in medicine. Primarily, it is used to diagnose and treat severe myasthenia gravis, a rare disease in which the transmission of nerve impulses to the muscles is disrupted, leading to a decrease in the strength of muscle contractions and the development of weakness. In myasthenia gravis, neostigmine may improve muscle function and reduce symptoms of the disease.

In addition, neostigmine is used as an antidote to reverse the effects of muscle relaxants, which are used during surgery to relax muscles and make surgery easier. Neostigmine can reverse the effect of relaxants, restoring muscle strength and tone.

Neostigmine may also be used to treat certain intestinal diseases, such as intestinal pseudo-obstruction, as well as to treat glaucoma. Depending on the indication, neostigmine can be administered orally, by injection or in eye drops.

Despite its widespread use in medicine, neostigmine can cause side effects such as digestive problems, nausea, vomiting and increased salivation. In this regard, it is necessary to strictly follow the doctor’s recommendations and not exceed the dosage of the medicine.

The trade name of neostigmine is Prostigmin. Although neostigmine is an effective drug, before you start using it, you should consult your doctor to determine the dosage and the possibility of use in each specific case.

Neostigmine is a parasympathomimetic drug that inhibits the action of the enzyme cholinesterase. It is used primarily for the diagnosis and treatment of severe pseudoparalytic myasthenia gravis. Neostigmine is also used as an antidote for certain drugs, such as muscle relaxants such as tubocurarine.

Neostigmine is also used to treat a number of intestinal diseases such as chronic colitis and irritable bowel syndrome. Additionally, it can be used as a treatment for glaucoma, which is one of the most common eye diseases.

Depending on the formulation, neostigmine can be taken orally, injected, or used as eye drops. However, like any other drug, neostigmine has its side effects, such as digestive problems and salivation, which can be caused by overdose or improper use.