Incompatibility Immunological

Immunological incompatibility

Immunological incompatibility is a condition in which the body's cells cannot interact with each other, which leads to a disruption of the immune system. This can be caused by various factors such as genetic mutations, infections, injuries and other diseases.

Immunological incompatibility can manifest itself in various forms. For example, when blood is transfused from a donor to a recipient, a rejection reaction may occur, which can lead to the death of the patient. This is because the immune system of the donor and recipient cannot interact properly due to incompatibility.

Immunological incompatibility can also occur during organ transplantation. If the recipient's immune system reacts to the transplant, this can lead to organ rejection and death of the patient.

To prevent immunological incompatibility, it is necessary to conduct a thorough diagnosis before performing surgeries and blood transfusions. It is also necessary to use treatments that reduce the rejection reaction.

Overall, immunological incompatibility is a serious problem that can lead to serious consequences for human health and life. Therefore, it is important to diagnose and treat this condition in the early stages to avoid complications.

Immunological incompatibility is a violation of the processes of interaction of antigens and antibodies with each other and with body tissues. This manifests itself in the form of complex pathological reactions that lead to the development of serious diseases.

For example, blood incompatibility according to the ABO system (antigens A, B and O) is often accompanied by complications during transfusion. Incompatibility of host and graft tissues is an obstacle to the engraftment of the donor organ. According to WHO, about 7% of organ transplant recipients die from complications of this reaction. The frequency of reactions depends on the nature of the incompatibility and its severity.

Immunological mismatch in newborns may be due to the following factors:

- Using the egg of a deceased person for fertilization; - Childbirth outside a medical facility;

The degree of inconsistencies, their nature

Immunological reactions are associated with pathological processes in the body, they need to be studied to prevent diseases with impaired immunity. Otherwise, immune cells can attack their own tissues. Incompatible in medicine is the body's reaction to a blood transfusion or organ transplantation as a result of a difference in the human antigens of the donor and recipient by more than 25%.