Nitrosorbid-N.s.

Nitrosorbid-N.S.

Country of origin - Russia
Pharm-Group - Antianginal agents - nitrates and nitrites

Manufacturers - Shchelkovo Vitamin Plant (Russia)
International name - Isosorbide dinitrate
Synonyms - Aerosonit, Dinit, Dinitrosorbilong, Ditrate, Iso Mac, Iso Mac retard, Izodinit, Izocard 20, Isocard 40, Isoket, Isolong, Izosorb retard, Isosorbide dinitrate retard, ISDN, Cardiket, Cardix, Cardicap, Cardiogard SR, Cardonite, Nisoperkuten , Nitrosorbide, Nitre
Dosage forms - tablets 10 mg
Composition - Active substance - Isosorbide dinitrate.

Indications for use: Angina pectoris (relief and prevention of attacks), acute myocardial infarction, acute left ventricular failure, hypertension, congestive heart failure.

Contraindications - Hypersensitivity, anemia, cerebral hemorrhage or recent head injury, glaucoma, hyperthyroidism, hypotension, pregnancy, lactation (breastfeeding must be stopped), childhood.

Side effects - Rush of blood to the face and neck, headache, nausea, vomiting, orthostatic hypotension, restlessness, tachycardia.

Interaction - Antihypertensive drugs (calcium antagonists, other vasodilators), tricyclic antidepressants, and alcohol increase hypotension, sympathomimetics reduce the antianginal effect.

Overdose - Symptoms: cyanosis of the lips and nails, severe dizziness or fainting, a feeling of pressure in the head, weakness, shortness of breath, weak and rapid heartbeat, elevated body temperature, convulsions. Treatment: symptomatic.

Special instructions - To prevent the development of tolerance (addiction), it is recommended that after 3-6 weeks of regular use, take a break for 3-5 days.

Literature:

1. Encyclopedia of Medicines 2003
2. Insert leaflet approved by the Directorate for the Introduction of New Medicines and Medical Equipment of the Ministry of Health of the Russian Federation on October 17, 1985.