Nonne-Apelt Reaction

Nonne-Appelte reaction
Nonne-Apelta is a pathophysiological reaction of the body to the introduction of a foreign agent. It was first described in 1904 by German neurologist Alfred Nonne and his wife Bertha Appelt.

The Nonne-Appelt reaction is characterized by a rapid and intense release of histamine into the blood, which leads to vasodilation, increased blood pressure, dilation of the bronchi and an increase in heart rate. This causes symptoms such as facial flushing, sweating, palpitations, dizziness, anxiety and fear.

The Nonne-Appelte reaction can be caused by various factors, such as stress, anxiety, exercise, alcohol or drug use, and certain medications. It plays an important role in regulating the body's homeostasis and adaptation to various environmental conditions.

Nonna-Apelt reaction is a rare congenital malformation that is characterized by malposition of the kidneys and uncontrolled muscle contractions caused by improper functioning of the neuromuscular system. This rare disease often occurs among young children. The first case of description of this disease was recorded in 1933, when the German psychiatrist and neurologist Gustav Geyers managed to observe a patient with Nonna Apelt reaction. After this, neurosurgeons began to notice the anomaly in many cases. Until now, research into this disease has been exceptionally sparse and only a few cases have been described. The disease can cause problems with urinary function