Obe coefficient

The obe coefficient is an important indicator that is used in medicine and biology to evaluate the relative biological effectiveness of various methods of treating or preventing diseases. It is an indicator of the ability of a single dose of a medicine or prophylactic to cure patients.

The obe coefficient is calculated based on the average value of the maximum concentrations of the drug in the blood after taking one dose of the drug. Further, using statistical indicators, these concentrations are compared with the same indicators when using placebo - the most

In nuclear energy, the Obe coefficient is used to study fuel homogeneity

(OE – volumetric absorption or volumetric efficiency). It is defined as the ratio of the leakage density kqi to the fuel density kt and depends on the amount of UO2 material and the geometry of the fuel sample. The Obe coefficient can be calculated using the formula:

OE = kr / kt, and also according to the OE formulas according to Kummerov and Shunkov:

COEk = 9.5 kq / (kt + kµ); COEsh = (kq - kd) / kt; (1) where COE is the volumetric absorption coefficient;