Country of origin - Germany
Pharm-Group - Agents that stimulate alpha and beta adrenergic receptors
Manufacturers - Goedecke/Parke-Davies (Germany)
International name - Xylometazoline
Synonyms - Brizolin, Galazolin, Grippostad Rino, Dlynos, Doctor Theiss Nazolin, Xylene, Xylobene, Xylometazoline, Xymelin, Nasal aerosol, Nazenspray E-ratiopharm, Nazenspray K-ratiopharm, Otrivin, Rhinonorm, Rinostop, Tizin xylo, Farmazolin
Dosage forms - nasal drops 0.05%, nasal drops 1%, solution 0.05%, solution 0.1%, nasal spray 0.1%
Composition - Active substance - xylometazoline.
Indications for use - Acute allergic rhinitis, hay fever, sinusitis, otitis media (to reduce swelling of the nasopharyngeal mucosa); preparing the patient for diagnostic procedures in the nasal passages.
Contraindications - Hypersensitivity, arterial hypertension, tachycardia, severe atherosclerosis, glaucoma, atrophic rhinitis, hyperthyroidism, pregnancy, breastfeeding.
Side effects - With frequent or prolonged use - irritation of the mucous membrane, burning, tingling, sneezing, dryness, hypersecretion. Rarely - swelling of the nasal mucosa, palpitations, heart rhythm disturbances, increased blood pressure, headache, vomiting, sleep disturbance, visual disturbances. With long-term use of high doses - depression.
Interaction - Incompatible with MAO inhibitors and tricyclic antidepressants.
Overdose - Symptoms: increased side effects. Treatment: symptomatic.
Special instructions - The aerosol is used in children under 3 years of age. Nasal drops with a concentration of the active substance of 1 mg/ml for children under 2 years of age are prescribed only by a doctor. Should not be used for a long time (for example, for chronic rhinitis). For colds, in cases where crusts form in the nose, it is preferable to administer it in the form of a gel.
Literature - 1. Encyclopedia of drugs 2004.